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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.12
- 수록면
- 1,639 - 1,648 (10page)
- DOI
- 10.13000/JFMSE.2019.12.31.6.1639
이용수
이 논문의 연구 히스토리 (2)
2019
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초록· 키워드
오류제보하기
In Megalocytivirus-persitently infected PMF cells (PI-PMF), the expression level of Mx gene was increased more than 20-fold, which was maintained consistently the same level through 7 days of subculture for passage. Moreover, although typical cytopathic effects (CPEs) of viral infections were observed in most of the cultured cells, the appearance of ladder-type DNA by cleavage of chromosomal DNA showing apoptosis was not confirmed. Both of these characteristics may be necessary factors for PI-PMF cells to be a persistent state of infection. By using limiting-dilution method analyzing the production of virus in each single cell, we figured out that approximately 9.4% of the cells in PI-PMF cell population exist as uninfected cells even in supernatant containing high density of virus during culture.
목차
Abstract
Ⅰ. 서론
Ⅱ. 연구 방법
Ⅲ. 연구 결과
Ⅳ. 결론
References
참고문헌 (15)
참고문헌 신청
Antoni BA / 1995 / Inhibition of Apoptosis in Human Immunodeficiency Virus-Infected Cells Enhances Virus Production and Facilitates Persistent Infection / Journal of Virology 69:2384~2392
Christopher Marlowe A Caipang / 2003 / In vitro inhibition of fish rhabdoviruses by Japanese flounder, Paralichthys olivaceus Mx / Virology 317(2):373~382
SC Chi / 2005 / Persistent infection of betanodavirus in a novel cell line derived from the brain tissue of barramundi Lates calcarifer / Diseases of Aquatic Organisms 65:91~98
Choi JC / 2016 / Preperation of Megalocytivirus Vaccine for Increased and Protective Effects on Rock bream (Oplegnathus fasciatus)
Masayuki Imajoh / 2007 / Characterization of a new fibroblast cell line from a tail fin of red sea bream, Pagrus major, and phylogenetic relationships of a recent RSIV isolate in Japan / Virus Research 126(1-2):45~52
Christopher Marlowe A Caipang / 2003 / In vitro inhibition of fish rhabdoviruses by Japanese flounder, Paralichthys olivaceus Mx / Virology 317(2):373~382
SC Chi / 2005 / Persistent infection of betanodavirus in a novel cell line derived from the brain tissue of barramundi Lates calcarifer / Diseases of Aquatic Organisms 65:91~98
Choi JC / 2016 / Preperation of Megalocytivirus Vaccine for Increased and Protective Effects on Rock bream (Oplegnathus fasciatus)
Masayuki Imajoh / 2007 / Characterization of a new fibroblast cell line from a tail fin of red sea bream, Pagrus major, and phylogenetic relationships of a recent RSIV isolate in Japan / Virus Research 126(1-2):45~52
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