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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.6
- 수록면
- 76 - 96 (21page)
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초록· 키워드
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Coronaviruses (CoVs) are the largest positive-sense RNA viruses with a wide range of natural hosts. To date, seven types of coronaviruses (HCoV-NL63; Human coronavirus NL63, HCoV-229E; Human coronavirus 229E, HCoV-OC43; Human coronavirus OC43, HCoV-HKU1; Human coronavirus HKU1, SARS-CoV; Severe acute respiratory syndrome-related coronavirus, MERS-Co; Middle East respiratory syndrome coronavirus, and SARS-CoV-2; Severe acute respiratory syndrome-related coronavirus) are known to cause disease in humans, and three of the CoVs (SARS-CoV, MERS-CoV, and SARS-CoV-2) cause severe, occasionally fatal, respiratory infections in humans. In November 2002, the case of severe acute respiratory syndrome (SARS), a new respiratory illness caused by SARS-CoV, was first reported in Guangdong Province, China. For the next several months, the SARS outbreak resulted in more than 8,000 cases of infection and 800 deaths. In June 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia with 2,373 reported viral infections and 823 associated deaths until February 2019. The outbreak of the MERS-CoV pandemic also occurred in South Korea in May 2015. In late December 2019, another novel coronavirus called SARS-CoV-2, genetically linked to SARS-CoV, emerged in Wuhan, Hubei Province of China that has spread worldwide. Outbreaks of coronavirus-infections are occurring frequently in the 21st century; therefore, it seems very likely that another pandemic of coronavirus can emerge anytime in the future. In this review, we outlined the biological characteristics of coronaviruses and summarized the status of vaccine development against SARS-CoV-2, SARS-CoV, and MERS-CoV in preparation for the unpredictable emergence of coronavirus pandemic.
목차
INTRODUCTION
CORONAVIRUSES
ANIMAL MODELS
VACCINE DEVELOPMENT
THE COVID-19 VACCINE DEVELOPMENT LANDSCAPE
FACTORS TO CONSIDER WHEN DEVELOPING COVID-19 VACCINE
DISCUSSION
REFERENCES
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Detection and Isolation of SARS-CoV-2 in Serum, Urine, and Stool Specimens of COVID-19 Patients from the Republic of Korea
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SARS-CoV-2 신속항원검사의 과제
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Pre-existing Immunity to Endemic Human Coronaviruses Does Not Affect the Immune Response to SARS-CoV-2 Spike in a Murine Vaccination Model
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Genomic Surveillance of SARS-CoV-2: Distribution of Clades in the Republic of Korea in 2020
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COVID-19 Outbreak in Malaysia
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SARS-CoV-2 Delta (B.1.617.2) Variant: A Unique T478K Mutation in Receptor Binding Motif (RBM) of Spike Gene
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Structure of SARS-CoV-2 Spike Glycoprotein for Therapeutic and Preventive Target
Immune Network
2021 .02
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감염병과 인류, 그리고 진화 : 『농경의 배신』, 제임스 스콧 지음/전경훈 옮김/책과함께/2019_『인수공통 모든 전염병의 열쇠』, 데이비드 콰먼 지음/강병철 옮김/꿈꿀자유/2017_『대혼란: 유전자 스와핑과 바이러스 섹스』, 앤드류 니키포룩 지음/이희수 옮김/알마/2010_『전염성 질병의 진화』, 폴 이월드 지음/이성호 옮김/아카넷/2014_『전염병과 인류의 역사』, 윌리엄 맥닐 지음/허정 옮김/한울/1992
박한선
황해문화
2020
.06
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UCI(KEPA) : I410-ECN-0101-2020-475-000892381