지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 278 - 285 (8page)
이용수
초록· 키워드
오류제보하기
ObjectiveTo prove the efficacy of determining the abnormal fetal cardiac axis for screening congenital heart defects (CHDs) andpredicting fetal aneuploidy at 11.0 to 13.6 weeks of pregnancy. MethodsThis retrospective study was performed at a single high-risk pregnancy center. The fetal cardiac axis was evaluatedbetween 11.0 and 13.6 weeks of gestation in 142 fetuses. The cardiac axis in a 4-chamber view was measured as theangle between the line tracing the long axis of the heart and the line bisecting the thorax in the anteroposteriordirection. A CHD was confirmed based on the second- to third-trimester fetal status or postnatal imaging. Aneuploidywas diagnosed using chorionic villus sampling, amniocentesis, or genetic testing after birth. Fisher’s exact test wasperformed to assess the association between the fetal cardiac axis and the abnormal fetal status. A 2-way contingencetable analysis was performed to confirm the efficacy of the fetal cardiac axis as a screening tool. ResultsAmong the 142 fetuses, 10 had a CHD while 17 had aneuploidy. The abnormal fetal cardiac axis was significantlyassociated with CHDs (P=0.013) and aneuploidy (P=0.010). None of the fetuses with CHDs or aneuploidy had anisolated abnormal cardiac axis alone without other sonographic findings. The sensitivity of the fetal cardiac axis was50.0% for CHDs and 41.2% for aneuploidy. ConclusionThe fetal cardiac axis can be an additional helpful tool for prenatal screening of CHDs and aneuploidy in the firsttrimester.
목차
등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Heron M / 2016 / Deaths : leading causes for 2014 / Natl Vital Stat Report 65:1~96
Donofrio MT / 2014 / Diagnosis and treatment of fetal cardiac disease : a scientific statement from the American Heart Association / Circulation 129:2183~2242
Souka AP / 2004 / Assessment of fetal anatomy at the 11–14-week ultrasound examination / Ultrasound Obstet Gynecol 24:730~734
Rasiah SV / 2006 / A systematic review of the accuracy of firsttrimester ultrasound examination for detecting major congenital heart disease / Ultrasound Obstet Gynecol 28:110~116
Kim GJ / 2017 / Why we do the 1st trimester echocardiography / Ultrasound Med Biol 43:S135
Donofrio MT / 2014 / Diagnosis and treatment of fetal cardiac disease : a scientific statement from the American Heart Association / Circulation 129:2183~2242
Souka AP / 2004 / Assessment of fetal anatomy at the 11–14-week ultrasound examination / Ultrasound Obstet Gynecol 24:730~734
Rasiah SV / 2006 / A systematic review of the accuracy of firsttrimester ultrasound examination for detecting major congenital heart disease / Ultrasound Obstet Gynecol 28:110~116
Kim GJ / 2017 / Why we do the 1st trimester echocardiography / Ultrasound Med Biol 43:S135
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