지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 601 - 610 (10page)
이용수
초록· 키워드
오류제보하기
Background: Currently, no generally accepted laboratory marker for monitorizing the disease activity and therapy response of psoriasis is known. Objective: The aim of the study is to evaluate the effects of systemic therapies on C-reactive protein (CRP) and the neutrophil-lymphocyte ratio (NLR) in psoriasis. Methods: One hundred patients with psoriasis treated with narrow band ultraviolet B, acitretin, cyclosporine, methotrexate, adalimumab, etanercept, and ustekinumab were prospectively evaluated. At baseline and at week 12, CRP, NLR, and Psoriasis Area and Severity Index (PASI) were evaluated. Results: A statistically significant decrease was observed in PASI scores, CRP, and NLR values from the baseline to the 12-week visit (p=0.001, p=0.001, p=0.001, respectively). The reduction in PASI scores and NLR values was positively correlated (r=0.460, p=0.001). The comparisons between treatment groups revealed that the median decrease in NLR values was statistically higher in the adalimumab group than in the methotrexate group (p=0.007). And the median decrease in PASI scores was significantly higher in the adalimumab group compared with the methotrexate and acitretin therapy group (p=0.007, p=0.042, respectively). Conclusion: In the present study, systemic therapy of psoriasis was demonstrated to decrease the levels of CRP and NLR, which are known to be indicators of systemic inflammation and cardiovascular comorbidities.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Biljan D / 2009 / Acute phase proteins in psoriasis / Coll Antropol 33:83~86
Langley RG / 2004 / Evaluating psoriasis with Psoriasis Area and Severity Index, Psoriasis Global Assessment, and Lattice System Physician's Global Assessment / J Am Acad Dermatol 51:563~569
Coimbra S / 2010 / C-reactive protein and leucocyte activation in psoriasis vulgaris according to severity and therapy / J Eur Acad Dermatol Venereol 24:789~796
Coimbra S / 2010 / Circulating adipokine levels in Portuguese patients with psoriasis vulgaris according to body mass index, severity and therapy / J Eur Acad Dermatol Venereol 24:1386~1394
Ctirad A / 2008 / Goeckerman’s therapy for psoriasis with special reference to serum pentraxin 3 level / Int J Dermatol 47:1011~1014
Langley RG / 2004 / Evaluating psoriasis with Psoriasis Area and Severity Index, Psoriasis Global Assessment, and Lattice System Physician's Global Assessment / J Am Acad Dermatol 51:563~569
Coimbra S / 2010 / C-reactive protein and leucocyte activation in psoriasis vulgaris according to severity and therapy / J Eur Acad Dermatol Venereol 24:789~796
Coimbra S / 2010 / Circulating adipokine levels in Portuguese patients with psoriasis vulgaris according to body mass index, severity and therapy / J Eur Acad Dermatol Venereol 24:1386~1394
Ctirad A / 2008 / Goeckerman’s therapy for psoriasis with special reference to serum pentraxin 3 level / Int J Dermatol 47:1011~1014
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
건선 환자 101명의 6개월간의 한의학적 치료효과에 대한 후향적 연구
한방안이비인후피부과학회지
2017 .01
-
건선의 한방치험 3례 - 보골지추출물을 병행하여
한방안이비인후피부과학회지
2018 .01
-
氣虛를 동반한 건선 환자 치험 2례
대한한의학회지
2016 .03
-
건선에서 사이클로스포린과 메토트렉세이트의 사용
대한건선학회지
2024 .06
-
기능성 위장장애를 동반한 건선 환자 치험 2례
한방안이비인후피부과학회지
2015 .01
-
Underlying liver disease and advanced stage liver cancer are associated with elevated neutrophil-lymphocyte ratio
Clinical and Molecular Hepatology
2019 .01
-
Treatment of Psoriasis with Exudation : Three Case Studies
대한한의학회지
2016 .06
-
만성신부전이 동반된 판상건선 환자의 생물학적제제 치료 3예
대한건선학회지
2021 .06
-
The Association between Psoriasis Area and Severity Index and Cardiovascular Risk Factor in Korean Psoriasis Patients
Annals of Dermatology
2016 .01
-
Factors Associated With Achieving Complete Skin Clearance Compared to Almost Complete Skin Clearance in Patients With Moderate to Severe Psoriasis Treated With Biologics: A Retrospective Chart Review
Annals of Dermatology
2024 .04
-
急性扁桃炎 이후 발생한 乾癬 환자 치험 4 례
대한한의학회지
2015 .09
-
The Relationship between Neutrophil-to-lymphocyte Ratio and Age-related Macular Degeneration
Korean Journal of Ophthalmology
2016 .01
-
상한론에 근거하여 오수유탕을 이용하여 호전된 건선 치험 1례
대한한의학방제학회지
2016 .01
-
Real-World Outcomes of Adalimumab Treatment for Moderate and Severe Psoriasis in Korean Patients (RAPSODI Study)
Annals of Dermatology
2023 .04
-
In which group of gastric cancer patients is the preoperative neutrophil-to-lymphocyte ratio a significant prognostic factor?
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2016 .06
-
Relation between the Peripherofacial Psoriasis and Scalp Psoriasis
Annals of Dermatology
2016 .01
-
Prevalence of Psoriasis in Korea: A Population-Based Epidemiological Study Using the Korean National Health Insurance Database
Annals of Dermatology
2017 .01
-
Preoperative neutrophil-to-lymphocyte ratio is a prognostic factor for overall survival in patients with gastric cancer
Annals of Surgical Treatment and Research
2015 .07
-
한의약 치료로 호전된 홍피성 건선 환자 치험 3례
한방안이비인후피부과학회지
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0