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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 1,103 - 1,107 (5page)
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The incidence of vaccine-type Streptococcus pneumoniae carriage and disease have declined in vaccinated children as well as in unvaccinatedchildren and adults. However, diseases caused by non-vaccine type (NVT) S. pneumoniae are increasing. In this study,we report an invasive pneumococcal disease (IPD) caused by NVT multidrug-resistant (MDR) S. pneumoniae transmitted from avaccinated infant to an unvaccinated healthy woman, and the clinical characteristics of this serotype. A 29-year-old previouslyhealthy woman visited our hospital with fever and headache. She had been breastfeeding her baby for 8 months. She was diagnosedwith brain abscess and sinusitis caused by S. pneumoniae. Although the patient had no previous exposure to antibiotics, antibioticsusceptibility test identified the pathogen as MDR. The patient’s family members were examined using nasopharyngeal swabs forbacterial culture. The serotype of S. pneumoniae identified from the blood, abscess, and sputum of the patient was 15B/C. After investingthe patient’s family members, we found that the serotype from nasopharyngeal specimen of her baby was the same. We describedan invasive MDR pneumococcal disease in an immunocompetent young adult in the community. IPD likely spread to thepatient by close contact with her baby, who harbored S. pneumoniae of NVT. The spread of NVT S. pneumoniae in the post-vaccineera has increased in the community, and resistance pattern for S. pneumoniae of 15B/C changed compared to the pre-pneumococcalconjugate vaccine era. The spread of MDR pathogens causing IPD among family members should be monitored.
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등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Walker CLF / 2013 / Global burden of childhood pneumonia and diarrhoea / Lancet 381:1405~1416
Wessels MR / 2015 / Harrison's principles of internal medicine / McGraw-Hill Education :963~970
이준기 / 2017 / Changes in the Serotype Distribution among Antibiotic Resistant Carriage Streptococcus pneumoniae Isolates in Children after the Introduction of the Extended-Valency Pneumococcal Conjugate Vaccine / Journal of Korean Medical Science 32(9):1431~1439
Bonten MJ / 2015 / Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults / N Engl J Med 372:1114~1125
최원석 / 2015 / Revised Adult Immunization Guideline Recommended by the Korean Society of Infectious Diseases, 2014 / Infection and Chemotherapy 47(1):68~79
Wessels MR / 2015 / Harrison's principles of internal medicine / McGraw-Hill Education :963~970
이준기 / 2017 / Changes in the Serotype Distribution among Antibiotic Resistant Carriage Streptococcus pneumoniae Isolates in Children after the Introduction of the Extended-Valency Pneumococcal Conjugate Vaccine / Journal of Korean Medical Science 32(9):1431~1439
Bonten MJ / 2015 / Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults / N Engl J Med 372:1114~1125
최원석 / 2015 / Revised Adult Immunization Guideline Recommended by the Korean Society of Infectious Diseases, 2014 / Infection and Chemotherapy 47(1):68~79
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