지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 129 - 136 (8page)
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Purpose: Routine screening for carotid intima-media thickness (CIMT) and cardiovascular (CV) disease in asymptomatic patientshas been criticized for the high costs and large number of patients required for detecting one patient with coronary artery disease(CAD). In order to overcome the low cost-effectiveness thereof, we investigated the feasibility of an economic wireless handheldultrasound (WHUS) device for CIMT measurement in symptomatic patients. Materials and Methods: A total of 100 consecutive patients with cardiac symptoms were enrolled. CIMT was measured in all patients. Coronary angiography was performed in 75 patients indicated for the exam. Results: The mean of maximal CIMT measured from left/right common carotid artery and bulb (max-CIMT) by the WHUS deviceshowed excellent agreement [intraclass correlation coefficient (ICC)=0.960] with a standard ultrasound device and great interobserverrepeatability (ICC>0.9 between all observers). Receiver operating characteristic curve analysis showed that the predictivepower for CAD was improved when max-CIMT and plaque information (plaque≥2) was added [area under the curve (AUC):0.838] to the traditional clinical CV risk factors (AUC: 0.769). The cutoff values for CAD prediction with the standard device and theWHUS device were 1.05 mm (AUC: 0.807, sensitivity: 0.78, specificity: 0.53) and 1.10 mm (AUC: 0.725, sensitivity: 0.98, specificity:0.27), respectively. Conclusion: max-CIMT measured by a WHUS device showed excellent agreement and repeatability, compared with standard ultrasound. Combined max-CIMT and plaque information added predictive power to the traditional clinical CV risk factors in detectinghigh-risk CAD patients.
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참고문헌 (20)
참고문헌 신청
Nambi V / 2010 / Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk : the ARIC(Atherosclerosis Risk In Communities)study / J Am Coll Cardiol 55:1600~1607
Cao JJ / 2007 / Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and allcause mortality : the Cardiovascular Health Study / Circulation 116:32~38
Øygarden H / 2017 / Carotid intima-media thickness and prediction of cardiovascular disease / J Am Heart Assoc 6:e005313
Zanchetti A / 2009 / Baseline values but not treatment-induced changes in carotid intima-media thickness predict incident cardiovascular events in treated hypertensive patients : findings in the European Lacidipine Study on Atherosclerosis(ELSA) / Circulation 120:1084~1090
최보금 / 2018 / Array Comparative Genomic Hybridization as the First-line Investigation for Neonates with Congenital Heart Disease: Experience in a Single Tertiary Center / Korean Circulation Journal 48(3):217~226
Cao JJ / 2007 / Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and allcause mortality : the Cardiovascular Health Study / Circulation 116:32~38
Øygarden H / 2017 / Carotid intima-media thickness and prediction of cardiovascular disease / J Am Heart Assoc 6:e005313
Zanchetti A / 2009 / Baseline values but not treatment-induced changes in carotid intima-media thickness predict incident cardiovascular events in treated hypertensive patients : findings in the European Lacidipine Study on Atherosclerosis(ELSA) / Circulation 120:1084~1090
최보금 / 2018 / Array Comparative Genomic Hybridization as the First-line Investigation for Neonates with Congenital Heart Disease: Experience in a Single Tertiary Center / Korean Circulation Journal 48(3):217~226
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