지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2000.1
- 수록면
- 17 - 19 (3page)
이용수
초록· 키워드
오류제보하기
Heterotrimeric G Proteins transduce ligand binding to a wide variety of seven transmembrane cell surface receptors into intracellular signals. The currently accepted model for the activation of G protein suggests that ligand-activated receptor accelerates GDP-GTP exchange reactions on the ${\alpha}$ subunit of the heterotrimeric G protein. At least seventeen distinct isoforms of the G${\alpha}$ subunit protein have been identified in mammalian organisms. Among them, the G${\alpha}$q family consists of five members whose ${\alpha}$ subunits show different expression patterns. G${\alpha}$q and G${\alpha}$11 seem to be almost ubiquitously expressed, whereas G${\alpha}$14 is predominantly expressed in spleen, lung, kidney and testis. G${\alpha}$16 and its murine counterpart G${\alpha}$15 are expressed in hematopoietic cells and has been shown to couple a wide variety of receptors to phosphoinositide-specific phospholipase C activity. Beta-isoforms of phospholipase C were shown to be activated by all members of G${\alpha}$q family, i.e., G${\alpha}$q, G${\alpha}$11, G${\alpha}$l4 and G${\alpha}$16 subunits either in reconstitution system. or in experiments using cDNA transfection with intact Cos-7 cells.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
New inhibitors of the NF-kB activation and NO production from Artemisia sylvatica
대한약학회 학술대회
2003 .01
-
An Efficient Synthesis of Cyclic $\alpha$, $\alpha$-Disubstituted $\alpha$-Amino Acids
대한약학회 학술대회
2001 .01
-
Microbial $9{\alpha}$-Hydroxylase:Epoxidation of 9(11)-dehydro-$17{\alpha}$-methyl-testosterone
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1997 .01
-
Interleukin-8 수용체와 G$_\alpha$ 16 subunit G protein 간의 분자상호 작용에 관한 연구
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2000 .01
-
Molecular interaction of $G{\alpha}16$ subunit G protein with chemoattractant receptors
대한약학회 학술대회
2002 .01
-
Direct Involvement of G Protein $\alpha_{q/11}$ Subunit in Regulation of Muscarinic Receptor-Mediated sAPP$\alpha$ Release
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
-
적출한 흰쥐 대동맥에 있어서 postsynaptic $\alpha_1$-, $\alpha_2$- 아드레날린 수용체에 관한 연구
약학회지
1986 .01
-
Frontal Alpha Asymmetry Correlates with Suicidal Behavior in Major Depressive Disorder
Clinical Psychopharmacology and Neuroscience
2019 .01
-
<sup>211</sup>At and <sup>211</sup>At-labeled radiopharmaceuticals for targeted alpha therapy
대한방사성의약품학회지
2018 .01
-
T 세포 하이브리도마에 의한 ${\alpha}2-Macroglobulin$의 생산
약학회지
1994 .01
-
Differential Coupling of G$\alpha$q Family of G-protein to Muscarinic $M_1$ Receptor and Neurokinin-2-Receptor
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1998 .01
-
Potential drug targets in the GPCR-$G{\alpha}_{12}/G{\alpha}_{13}$ signaling pathways
한국응용약물학회 춘계학술발표논문집
2008 .01
-
$(\pm)-\alpha-Hydroxy-\alpha$-(p-Chlorobiphenyl)acetic acid 합성과 분할
약학회지
1995 .01
-
Brain Alpha Rhythm Component in fMRI and EEG
의공학회지
2005 .01
-
폐암세포주의 TNF-$\alpha$ 유발 apoptosis에서 NF-${\kappa}B$의 역할
Tuberculosis and Respiratory Diseases
2000 .01
-
Stereoselective synthesis of novel 4′$\alpha$-C-methyl branched novel carbocyclic nucleosides
대한약학회 학술대회
2002 .01
-
Cholesterol, L-$\alpha$-Phosphatidylinositol, L-$\alpha$-Phosphatidylserine을 함유한 L-$\alpha$-Dimyristoyl-phosphatidyl Choline 리포솜에 대한 Phospholipase D의 작용에 관한 연구
약학회지
1983 .01
-
Constrained Independent Component Analysis Based Extraction and Mapping of the Brain Alpha Activity in EEG
의공학회지
2008 .01
-
Administration of Alpha<sub>s1</sub>-Casein Hydrolysate Increases Sleep and Modulates GABA<sub>A</sub> Receptor Subunit Expression
Biomolecules & Therapeutics(구 응용약물학회지)
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0