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자료유형
학술저널
저자정보
Yi, Jin-Mu (Department of Oriental Pharmacy, College of Pharmacy, and Center of Oriental Medicinal Science, Wonkwang University) Jeong, Hyun-Ja (Department of Oriental Pharmacy, College of Pharmacy, and Center of Oriental Medicinal Science, Wonkwang University) Shim, Kyung-Shik (Department of Oriental Pharmacy, College of Pharmacy, and Center of Oriental Medicinal Science, Wonkwang University) Lee, Kang-Yong (Department of Oriental Pharmacy, College of Pharmacy, and Center of Oriental Medicinal Science, Wonkwang University) Kim, Jeong-Sook (Department of Oriental Pharmacy, College of Pharmacy, and Center of Oriental Medicinal Science, Wonkwang University) Zheng, Cui (Shenyang pharmacenfical University) Tomoko, Jippo (Department of Pathology, Osaka University Medical school) Lee, Young-Mi (Department of Oriental Pharmacy, College of Pharmacy, and Center of Oriental Medicinal Science, Wonkwang University)
저널정보
경희한의학연구센터 International journal of oriental medicine : OM International journal of oriental medicine : OM 제1권 제2호
발행연도
2000.1
수록면
21 - 28 (8page)

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We compared the effect between CAS and WAS(root, stem) on mast cell-mediated allergic reaction. CAS, WAS-root and WAS-stem, significantly inhibited compound 48/80-induced systemic allergic reaction(1g/kg) and histamine release from RPMC(1mg/ml). CAS, WAS-root and WAS-stem also inhibited passive cutaneous anaphylactic reaction. In addition, IgE-induced $TNF-{\alpha}$ secretion from RBL-2H3 was inhibited by pretreatment of CAS, WAS-root or WAS-stem$(0.01{\mu}g/ml)$. Taken together, inhibitory effect on mast cell-mediated allergic reactions of WAS-root is greater than those of WAS-stem but less than those of CAS.

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