지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제22권 제1호
- 발행연도
- 1999.1
- 수록면
- 1 - 8 (8page)
이용수
초록· 키워드
오류제보하기
Transforming growth factor-$\beta$ (TGF-$\beta$) is the prototypical multifunctional cytokine, participating in the regulation of vital cellular activities such as proliferation and differentiations as well as a number of basic physiological functions. The effects of TGF-$\beta$ are critically dependent on the expression and distribution of a family of TGF-$\beta$ receptors, the TGF-$\beta$ types I, II, and III. It is now known that a wide variety of human pathology can be caused by aberrant expression and function of these receptors. the coding sequence of the type II receptor (RII) appears to render it uniquely susceptible to DNA replication errors in the course of normal cell division. By virtue of its key role in the regulation of cell proliferation, TGF-$\beta$ RII should be considered as a tumor suppressor gene. High levels of mutation in the TGF-$\beta$ RII gene have been observed in a wide range of primarily epithelial malignancies, including colon and gastric cancer. It appears likely that mutation of the TGF-$\beta$ RII gene may be a very critical step in the pathway of carcinogenesis.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A Sensitive Bioassay Method For Measuring Antoproliferative Activity of Transforming Growth Factor ${\beta}(TGF-{\beta})$
대한약학회 학술대회
2001 .01
-
흰쥐 초산 유도 십이지장 궤양 치유과정에서 TGF-beta 및 그 수용체의 발현
Journal of Pathology and Translational Medicine
2003 .01
-
장형화생, 위선종 및 위암에서 TGF-βⅠ과 TGF-β Receptor Ⅱ (TGF-βRII) 발현의 의의
Annals of Surgical Treatment and Research
2001 .05
-
대장 선종 및 대장 선암에서 TGF-β1, 제2형 TGF-β 수용체 및 VEGF 단백의 면역조직화학적 발현
Clinical Endoscopy
2007 .01
-
초음파가 흰쥐 아킬레스건 손상부위의 $TGF-\beta$발현에 미치는 영향
대한물리치료학회지(JKPT)
2002 .01
-
Transforming Growth Factor-$\beta$ (TGF)-$\beta$, Induces Invasion and Migration of MCF10A Human Breast Epithelial Cells
대한약학회 학술대회
2003 .01
-
Effect of Soy Isoflavones on the Expression of TGF-β1 and Its Receptors in Cultured Human Breast Cancer Cell Lines
대한의생명과학회지
2005 .06
-
Role of the transforming growth factor (TGF)-β1 and TGF-β1 signaling pathway on the pathophysiology of respiratory pneumococcal infections
영남의대학술지
2017 .01
-
Proinflammatory Cytokines과 TGF-beta가 섬유모세포의 증식에 미치는 영향
Tuberculosis and Respiratory Diseases
1998 .01
-
정신분열병 환자에서 Interleukin-12와 Transforming Growth Factor Beta 1의 치료 전후의 변화
생물정신의학
2005 .01
-
Role of Transforming Growth Factor-β in Tumor Invasion and Metastasis
Toxicological Research
2007 .09
-
Role of TGF-β1 in Human Colorectal Cancer and Effects after Cantharidinate Intervention
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
Beta-lg H3을 이용한 사람 골수 중배엽 줄기세포의 연골분화 유도
대한정형외과학회지
2004 .08
-
Cell Growth of BG-1 Ovarian Cancer Cells was Promoted by 4-Tert-octylphenol and 4-Nonylphenol via Downregulation of TGF-β Receptor 2 and Upregulation of c-myc
Toxicological Research
2011 .12
-
Balb/C mouse의 폐장대식세포에서 유리규산 자극에 의한 Proinflammatory Cytokine과 TGF-$\beta$의 생성 및 상관관계
Tuberculosis and Respiratory Diseases
1998 .01
-
쥐의 폐에서 방사선이 Nitric Oxide (NO), Nitric Oxide Synthase (NO) 및 TGF- $\beta$의 발현에 미치는 영향
Radiation oncology journal : ROJ
2000 .01
-
Overview of Transforming Growth Factor β Superfamily Involvement in Glioblastoma Initiation and Progression
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
내독소에 의한 말초혈액 단핵구의 IL-1beta, IL-6, TNF-alpha와 TGF-beta 생성에 관한 연구
Tuberculosis and Respiratory Diseases
1998 .01
-
Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy
Biomolecules & Therapeutics(구 응용약물학회지)
2013 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0