지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Streptococcus pneumoniae, pneumococcus, is the most common cause of community-acquired pneumonia (CAP). CAP is an important infectious disease with high morbidity and mortality, and it is still one of the leading causes of death worldwide. Many genetic factors of the host and various environmental factors surrounding it have been studied as important determinants of the pathophysiology and outcomes of pneumococcal infections. Various cytokines, including transforming growth factor $(TGF)-{\beta}1$, are involved in different stages of the progression of pneumococcal infection. $TGF-{\beta}1$ is a cytokine that regulates a wide range of cellular and physiological functions, including immune and inflammatory responses. This cytokine has long been known as an anti-inflammatory cytokine that is critical to preventing the progression of an acute infection to a chronic condition. On the other hand, recent studies have unveiled the diverse roles of $TGF-{\beta}1$ on different stages of pneumococcal infections other than mitigating inflammation. This review summarizes the recent findings of the role of $TGF-{\beta}1$ on the pathophysiology of pneumococcal infections, which is fundamental to developing novel therapeutic strategies for such infections in immune-compromised patients.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Role of the transforming growth factor (TGF)-β1 and TGF-β1 signaling pathway on the pathophysiology of respiratory pneumococcal infections
Journal of Yeungnam Medical Science
2017 .01
-
The prevention of pneumococcal infections
Clinical and Experimental Vaccine Research
2016 .01
-
Recent Advances in the Development of TGF-β Signaling Inhibitors for Anticancer Therapy
대한암예방학회지
2020 .01
-
Overview of Transforming Growth Factor β Superfamily Involvement in Glioblastoma Initiation and Progression
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling
Biomolecules & Therapeutics(구 응용약물학회지)
2017 .01
-
Crosstalk Signaling between IFN-γ and TGF-β in Microglia Restores the Defective β-amyloid Clearance Pathway in Aging Mice with Alzheimer’s Disease
대한의생명과학회지
2018 .12
-
Increased Expression of TGF-β1 in Correlation with Liver Fibrosis during Echinococcus granulosus Infection in Mice
Parasites, Hosts and Diseases
2016 .08
-
The Role of Tripartite Motif Family Proteins in TGF-β Signaling Pathway and Cancer
대한암예방학회지
2018 .01
-
Effect of PHMG-P on TGF-β mediated signaling pathways in animal models
환경독성보건학회 심포지엄 및 학술대회
2019 .10
-
Differential Role of Transforming Growth Factor-beta in an Osteoarthritic or a Healthy Joint
대한골대사학회지
2018 .01
-
Cardamonin Suppresses TGF-β1-Induced Epithelial Mesenchymal Transition via Restoring Protein Phosphatase 2A Expression
Biomolecules & Therapeutics(구 응용약물학회지)
2015 .01
-
Recent Trends in Invasive Pneumococcal Disease in Korea in the Post-pneumococcal Vaccine Era
Annals of Laboratory Medicine
2023 .01
-
Acute Effects of Transforming Growth Factor-1 on Neuronal Excitability and Involvement in the Pain of Rats with Chronic Pancreatitis
Journal of Neurogastroenterology and Motility (JNM)
2016 .01
-
Apolipoprotein A1 Inhibits TGF-β1-Induced Epithelial-to-Mesenchymal Transition of Alveolar Epithelial Cells
Tuberculosis and Respiratory Diseases
2016 .01
-
TGF-β Suppresses COX-2 Expression by Tristetraprolin-Mediated RNA Destabilization in A549 Human Lung Cancer Cells
Cancer Research and Treatment
2015 .01
-
Increased Serum Endoglin and Transforming Growth Factor β1 mRNA Expression and Risk of Hepatocellular Carcinoma in Cirrhotic Egyptian Patients
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Effect of PHMG-p on TGF-β mediated signaling pathways in vivo and in vitro
환경독성보건학회 심포지엄 및 학술대회
2019 .04
-
Parthenolide inhibits transforming growth factor β1induced epithelial-mesenchymal transition in colorectal cancer cells
Intestinal research
2019 .01
-
The TGF-b1 Signaling Pathway According to Lauren"s Classification in Gastric Cancer
대한임상종양학회 학술대회지
2015 .02
이 논문의 저자 정보
최근 본 자료
댓글(0)
0