Cost-Effectiveness Analysis for National Dyslipidemia Screening Program in Korea: Results of Best Case Scenario Analysis Using a Markov Model

Kim, Jae-Hyun; Park, Eun-Cheol; Kim, Tae-Hyun; Nam, Chung-Mo; Chun, Sung-Youn; Lee, Tae-Hoon; Park, Sohee

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자료유형: 학술저널

저자정보: Kim, Jae-Hyun (Department of Health Administration, Dankook University College of Health Science) Park, Eun-Cheol (Department of Preventive Medicine, Yonsei University College of Medicine) Kim, Tae-Hyun (Institute of Health Services Research, Yonsei University) Nam, Chung-Mo (Department of Preventive Medicine, Yonsei University College of Medicine) Chun, Sung-Youn (Institute of Health Services Research, Yonsei University) Lee, Tae-Hoon (Institute of Health Services Research, Yonsei University) Park, Sohee (Institute of Health Services Research, Yonsei University)

저널정보: 한국보건행정학회 보건행정학회지 보건행정학회지 제29권 제3호

발행연도: 2019.1

수록면: 357 - 367 (11page)

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Background: This study evaluated the cost-effectiveness of 21 different national dyslipidemia screening strategies according to total cholesterol (TC) cutoff and screening interval among 40 years or more for the primary prevention of coronary heart disease over a lifetime in Korea, from a societal perspective. Methods: A decision tree was used to estimate disease detection with the 21 different screening strategies, while a Markov model was used to model disease progression until death, quality-adjusted life years (QALYs) and costs from a Korea societal perspective. Results: The results showed that the strategy with TC 200 mg/dL and 4-year interval cost \4,625,446 for 16.65105 QALYs per person and strategy with TC 200 mg/dL and 3-year interval cost \4,691,771 for 16.65164 QALYs compared with \3,061,371 for 16.59877 QALYs for strategy with no screening. The incremental cost-effectiveness ratio of strategy with TC 200 mg/dL and 4-year interval versus strategy with no screening was \29,916,271/QALY. At a Korea willingness-to-pay threshold of \30,500,000/QALY, strategy with TC 200 mg/dL and 4-year interval is cost-effective compared with strategy with no screening. Sensitivity analyses showed that results were robust to reasonable variations in model parameters. Conclusion: In this study, revised national dyslipidemia screening strategy with TC 200 mg/dL and 4-year interval could be a cost-effective option. A better understanding of the Korean dyslipidemia population may be necessary to aid in future efforts to improve dyslipidemia diagnosis and management.

#Cost #Dyslipidemia #Effectiveness #Screening

참고문헌 (30)

참고문헌 신청

Li YH / 2002 / Serum cholesterol changes from 1983-1984 to 1993-1994 in the People’s Republic of China / Nutr Metab Cardiovasc Dis 12(3):118~126

Sekikawa A / 1999 / Coronary heart disease mortality trends in men in the post World War II birth cohorts aged 35-44 in Japan, South Korea and Taiwan compared with the United States / Int J Epidemiol 28(6):1044~1049

노은 / 2013 / Prevalence and Management of Dyslipidemia in Korea:Korea National Health and Nutrition Examination Survey during 1998 to 2010 / Diabetes and Metabolism Journal 37(6):433~449

Sun Ha Jee / 2014 / A coronary heart disease prediction model: the Korean Heart Study / BMJ Open 4(5):e005025

Paul A. Heidenreich / 2011 / Forecasting the Future of Cardiovascular Disease in the United States / Circulation 123(8):933~944

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김재현

소속기관 단국대학교

주요연구분야 사회과학 > 경영학 사회과학 > 사회학

논문수 20 이용수 2,886

Eun Cheol Park

소속기관 연세대학교

주요연구분야 의약학 > 의학 일반 의약학 > 기초의학 > 예방의학·직업환경의학

논문수 62 이용수 1,635

Kim, Tae Hyun

소속기관 Institute of Health Services Research, Yonsei University