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This study aimed to investigate the anti-obesity effects of yogurt fermented by Lactobacillus plantarum Q180 in diet-induced obese rats. To examine the effects, male Sprague-Dawley rats were fed on six different diets, as follows: Group A was fed an ND and orally administrated saline solution; Group B, an HFD and orally administrated saline solution; Group C, an HFD and orally administrated yogurt fermented by ABT-3 and L. plantarum Q180; Group D, an HFD and orally administrated yogurt with added Garcinia cambogia extract, fermented by ABT-3 and L. plantarum Q180; Group E, an HFD and orally administrated yogurt fermented by L. plantarum Q180; and Group F, an HFD and orally administrated yogurt with added Garcinia cambogia extract, fermented by L. plantarum Q180 for eight weeks. After eight weeks, the rate of increase in bodyweight was 5.14%, 6.5%, 3.35% and 10.81% lower in groups C, D, E and F, respectively, compared with group B; the epididymal fat weight of groups E and F was significantly lower than that of group B; and the level of triglyceride and leptin was significantly reduced in groups C, D, E and F compared to group B. In addition, the level of AST was reduced in group C compared to the other groups. To examine the effects of yogurt on the reduction of adipocyte size, the adipocyte sizes were measured. The number of large-size adipose tissue was less distributed in groups A, C, D, E and F than in group B.
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참고문헌 (31)
참고문헌 신청
Adolfsson, O. / 2004 / Yogurt and gut function / Am. J. Clin. Nutr 80:245~256
Arita, Y. / 1999 / Paradoxical decrease of an adiposespecific protein, adiponectin, in obesity / Biochem. Biophys. Res. Commun 257:79~83
Axelsson, R. / 1998 / Lactic acid bacteria: Microbiology and functional aspects / Marcel Dekker Inc :1~53
Jasmine Bhathena / 2009 / Orally Delivered Microencapsulated Live Probiotic Formulation Lowers Serum Lipids in Hypercholesterolemic Hamsters / Journal of Medicinal Food 12(2):310~319
Cani, P. D. / 2007 / Metabolic endotoxemia initiates obesity and insulin resistance / Diabetes 56:1761~1772
Arita, Y. / 1999 / Paradoxical decrease of an adiposespecific protein, adiponectin, in obesity / Biochem. Biophys. Res. Commun 257:79~83
Axelsson, R. / 1998 / Lactic acid bacteria: Microbiology and functional aspects / Marcel Dekker Inc :1~53
Jasmine Bhathena / 2009 / Orally Delivered Microencapsulated Live Probiotic Formulation Lowers Serum Lipids in Hypercholesterolemic Hamsters / Journal of Medicinal Food 12(2):310~319
Cani, P. D. / 2007 / Metabolic endotoxemia initiates obesity and insulin resistance / Diabetes 56:1761~1772
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