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논문 기본 정보

자료유형
학술저널
저자정보
Choi, Seong-Kwan (Dept. of Radiological Science, Hanlyo University) Jung, Woon-Kwan (Dept. of Nuclear Energy Technology, Chosun University) Lee, Kyu-Soo (Dept. of Radiological Science, Hanlyo University) Jang, Young-Il (Dept. of Radiological Technology, Kwangysng Health College) Dong, Kyeong-Rae (Dept. of Radiological Technology, Kwangysng Health College)
저널정보
대한방사선방어학회 방사선방어학회지 방사선방어학회지 제32권 제4호
발행연도
2007.1
수록면
134 - 139 (6page)

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In order to find out the Radioprotective effect of algin-oligosaccharide(AOS), this study, with a mouse of which whole frame irradiated by 3 Gy radiation once, measured caspase-3 and caspase-9 amid cell signaling connected to apoptosis in order to observe cell activation. In Caspase-3 and Caspase-9 test for observing cell activation, both of Caspase-3 and Caspase-9 showed highly increased O.D. value in the irradiation control group, while the whole groups treated with algin-oligosaccharide before or after irradiation indicated lower O.D. value than the irradiation control group, especially showed big difference in 7 day's treatment group of before irradiation (P<0.001). It confirmed that Caspase generation was restrained in AOS treatment group. Consequently, this study inquired into the fact that algin-oligosaccharide with superior antioxidant activity performed radiation protection by inducing restraint of Caspase generation and confirmed that natural product with less chemical toxicity was able to be applied as radioprotector.

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