지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
With the improvement in the standard of living and extension of life expectancy, the incidence of prostate diseases has increased yearly, thus becoming a serious disease affecting the health of men. The extract mixture of Cornus officinalis and Stauntonia hexaphylla leaves is a developed functional food formula to improve prostate health. This study developed a simultaneous analytical method of bioactive compounds for quantifying the mixture of Cornus officinalis and S. hexaphylla leaves using high-pressure liquid chromatography-ultraviolet (HPLC–UV). HPLC analytical condition was performed on a Hector C<SUB>18</SUB> column with a mobile phase of 0.1 % formic acid in water (A) and 0.1 % formic acid in acetonitrile (B) under the following gradient conditions:0-50 min, 12 %-40 % (B) at a flow rate of 1.0 mL/min. Meanwhile, this method was validated properly and successfully used to quantify the bioactive components of morroniside and hederacoside D in 20 sample batches and assess the quality of different ages and seasons of S. hexaphylla leaves. The result showed that the content of morroniside in the extract mixture of Cornus officinalis and S. hexaphylla leaves ranged from 1.38-1.62 mg/g, and the hederacoside D ranged from 28.42-32.02 mg/g, suggesting that this novel analytical method will be suitable for the quality control of the extract mixture to improve benign prostatic hyperplasia.
목차
Abstract
1. Introduction
2. Experimental
3. Results and Discussion
4. Conclusions
References
참고문헌 (12)
참고문헌 신청
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H. K. Bhakta, C. H. Park, T. Yokozawa, T. Tanaka, H. A. Jung and J. S. Choi, Arch. Pharm. Res., 40(7), 836- 853 (2017).
F. Malongane, L. J. McGaw and F. N. Mudau, J. Sci. Food Agric., 97(14), 4679-4689 (2017).
C.-H. Tsai, S.-F. Tzeng, S.-C. Hsieh, Y.-C. Yang, Y.-W. Hsiao, M.-H. Tsai and P.-W. Hsiao, Sci. Rep., 7(1), 1-14 (2017).
J. Y. Jung, S. S. L. Karunasagara, G. L. Hong, E. J. Koh, K. W. Cho, S. S. Park and K. H. Kim, BioRxiv, 819474 (2019) https://doi.org/10.1101/819474.
H. K. Bhakta, C. H. Park, T. Yokozawa, T. Tanaka, H. A. Jung and J. S. Choi, Arch. Pharm. Res., 40(7), 836- 853 (2017).
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