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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.5
- 수록면
- 48 - 48 (1page)
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Aging leads to structural changes and functional impairment of the kidneys. Renal proximal tubule is the ‘workhorse’ of the kidney because it reabsorbs bulk amount of ions and water from the filtrate. The purpose of this study is to examine the effects of aging on the proximal tubule ultrastructure and water reabsorption in the aging kidney. Kidney tissues from young (2 months old) and elderly (20 month) C57BL/6 mice were processed for light and electron microscopy. In the young mouse kidney, the cytoplasm of the proximal tubule cells was densely packed with mitochondria and had extensive lateral interdigitations between neighboring cells. The apical surface was covered with numerous microvilli to form the characteristic brush border. Aquaporin-1 (AQP1) is the principal water ... 전체 초록 보기
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