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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 90 - 90 (1page)
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Low permeability featuring the central nervous system (CNS) vessels is established by enhanced tight junction and suppressed transcytosis of endothelial cells. While the players for barriergenesis of CNS vessels have been identified, most all corresponding knockout mice showed severe hemorrhagic phenotypes complicating the analysis of specific mechanisms underlying tight junction integrity and limited transcytosis. On the other hand, how the low permeability of CNS vessels is maintained during adulthood remains unknown.
Dll4 signaling has a number of roles in vascular development but its contribution to the low vascular permeability of CNS tissues has been unknown. We found that Dll4 is persistently and specifically expressed in arteries of adult retina, one ... 전체 초록 보기
Dll4 signaling has a number of roles in vascular development but its contribution to the low vascular permeability of CNS tissues has been unknown. We found that Dll4 is persistently and specifically expressed in arteries of adult retina, one ... 전체 초록 보기
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