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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 184 - 184 (1page)
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Lung cancer, known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung. It is the leading cause of cancer deaths worldwide, and progresses faster than other cancer and is often asymptomatic until the disease progresses. The anticancer drugs can inhibit cancer cell growth, but the prognosis is poor due to frequent recurrences that are resistant to the treatments. In this study, we identified a gene GCC2 altering the properties of cancer cells, which is a protein in trans-Golgi membrane that appears to regulate endoplasmic reticulum transport between endosomes and the Golgi apparatus. In our cell culture experiments using the lung cancer cell lines, the shRNA was applied to the cell lines to suppress the expression of the GCC2 gene. Int ... 전체 초록 보기
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