메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색
질문

논문 기본 정보

자료유형
학술대회자료
저자정보
Muhammad Imran KHAN (Chonnam National University) Muhammad Zubair KHAN (Chonnam National University) Jin Hyuk SHIN (Chonnam National University) Ji Hyeon LEE (Chonnam National University) Seong Whan CHO (Chonnam National University) Tia Sun SHIN (Chonnam National University) Min Yong KIM (Chonnam National University) Jong Deog KIM (Chonnam National University)
저널정보
한국생물공학회 한국생물공학회 학술대회 2021 한국생물공학회 추계학술발표대회 및 국제심포지엄 [초록집]
발행연도
2021.10
수록면
619 - 619 (1page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색
질문

이 논문의 연구 히스토리 (15)

2021

Amelioration of Tauopathy via Suppression of Tau Hyperphosphorylation by Reducing the Expression Level of Various Involved Genes and Kinesis with Theasaponin E1, A Therapeutic Target for Alzheimer’s Treatment Attenuation of Obesity with Synergistic Therapeutic and Preventive Effects of Natural Products by Suppression of Associated Promoting Signaling Pathways Attenuation of Obesity with Synergistic Therapeutic and Preventive Effects of Natural Products by Suppression of the Associated Promoting Signaling Pathways Amelioration of Taupathy via Suppression of Tau Hyperphosphorylation by Reducing the Expression Level of Various Involved Genes and Kinesis with Theasaponin E1, a Therapeutic Target for Alzheimer’s Treatment Amelioration of Angiogenesis, Adipogenesis and Lipogenesis to Attenuate Obesity by Targeting the Associated Promoting Signaling Molecules and Transcriptional Factors with Combination of Theasaponin E1, Stevioside and Rebaudioside A in Obesity Model Cells and Animals

초록· 키워드

오류제보하기
Alzheimer disease (AD) is neurodegenerative disorder and principal type of dementia. Formation of extracellular senile plaques and cytoplasmic neurofibrillary tangles (NFT) in brain due to the abnormal production and aggregation of amyloid beta (Aß) and tau proteins are the major molecular cause of AD. Paired helical filaments (PHF) are formed due to hyperphosphorylation of tau leads to formation of NFT which accumulate, and aggregates causing pathological conditions and eventually cause neuronal death. Tau phosphorylation is controlled by several genes and proteins. Several kinesis such as GSK3 beta, CDK5 and CAMII, etc are involved in phosphorylation of tau and phosphatases such as PH1A, PH1B etc are involved in dephosphorylation of tau, the imbalance of which leads to hyperphosphorylation and finally NFT. In this study we elucidate the effects of theasponin E1 on the activities andgene’s expression level of kinases and phosphatases involved in the phosphorylation and dephosphorylation of tau. The ther-apeutic neuroprotective effects of green tea seed isolated theasaponin E1 was examine usin ... 전체 초록 보기

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0