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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 658 - 658 (1page)
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이 논문의 연구 히스토리 (3)
2021
Development of Gut-mucus Chip Mimicking Intestinal Mucosa for Intestinal Absorption Study
Seung Yeon LEE
,
Seo Jin PARK
,
Ui Jung HWANG
외 5명
한국생물공학회 학술대회
2021.10
학술대회자료
Development of Gut-mucus Chip for Intestinal Absorption Study
Seung Yeon LEE
,
Yeon Jae KANG
,
Bum Sang KIM
외 2명
한국생물공학회 학술대회
2021.04
학술대회자료
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The intestinal mucosa acts as a barrier to protect the intestinal cells from foreign substances and interferes with drug delivery. The Caco-2 based cell culture model is a standard in vitro model system for testing drug uptake. However, it is difficult to say that it reflects the actual delivery of drugs in the intestine because it does not consider the effect of the mucous membrane. Here, we developed a microfluidic embedded chip using Caco-2 cells coated with mucin protein. It was observed that the coated mucin layer was maintained under the flow conditions. In addition, the role of the mucus l ... 전체 초록 보기
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