지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Objective. Trauma has been proposed as a triggering factor of psoriatic arthritis (PsA), and the deep Koebner phenomenon was the suggested underlying mechanism. The relationship between spondyloarthritis (SpA) and trauma was only observed in PsA. This study investigated cases of SpA other than PsA that occurred after physical trauma and analyzed their clinical, laboratory, and radiologic features. Methods. We retrospectively reviewed the medical records of 213 patients who visited our hospital due to a suspicion of SpA and grouped them into post-traumatic-SpA (PT-SpA, n=12) and non-post-traumatic-SpA (non-PT-SpA, n=201). Baseline characteristics were compared between the two groups by cross-sectional manner. Results. Peripheral SpA was more common in PT-SpA than in non-PT-SpA. Active inflammation on sacroiliac joint (SIJ) magnetic resonance imaging (MRI) was more common in non-PT-SpA (83.5% vs. 54.5%, p=0.046). The modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) was significantly higher in the non-PT-SpA group (2.0 vs. 0.0, p=0.007). Symptom duration from the first SpA symptom to diagnosis tends to be longer in the non-PT-SpA group (2.0 vs. 0.5 years, p=0.079). Conclusion. PT-SpA patients more frequently showed peripheral SpA, a less active inflammatory lesion on SIJ MRI, and a lower mSASSS score. Further studies are needed to clarify whether physical trauma has a direct/indirect role in the pathogenesis of SpA or merely confers an opportunity to recognize SpA symptoms.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Sieper J / 2009 / The Assessment of SpondyloArthritis international Society(ASAS)handbook : a guide to assess spondyloarthritis / Ann Rheum Dis 68(Suppl 2):ii1~ii44
Ranganathan V / 2017 / Pathogenesis of ankylosing spondylitis-recent advances and future directions / Nat Rev Rheumatol 13:359~367
Van Mechelen M / 2016 / Microtrauma : no longer to be ignored in spondyloarthritis / Curr Opin Rheumatol 28:176~180
Jacques P / 2014 / Proof of concept : enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells / Ann Rheum Dis 73:437~445
Thorarensen SM / 2017 / Physical trauma recorded in primary care is associated with the onset of psoriatic arthritis among patients with psoriasis / Ann Rheum Dis 76:521~525
Ranganathan V / 2017 / Pathogenesis of ankylosing spondylitis-recent advances and future directions / Nat Rev Rheumatol 13:359~367
Van Mechelen M / 2016 / Microtrauma : no longer to be ignored in spondyloarthritis / Curr Opin Rheumatol 28:176~180
Jacques P / 2014 / Proof of concept : enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells / Ann Rheum Dis 73:437~445
Thorarensen SM / 2017 / Physical trauma recorded in primary care is associated with the onset of psoriatic arthritis among patients with psoriasis / Ann Rheum Dis 76:521~525
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