지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 203 - 215 (13page)
이용수
초록· 키워드
오류제보하기
Background The identification of genomic regions under selection can potentially permit a better understanding of the biology of the specific phenotypes which are useful for the development of tools designed to increase selection efficiency. Objective The aim of this study was to detect any traces of recent selection signatures as well as to identify corresponding genes and QTLs underlying these selection signatures in Sarabi cattle. Methods Samples from 20 animals were genotyped for 777,962 SNPs across the genome using the Illumina BovineHD BeadChip. Selection signatures analysis was performed using the integrated haplotype score (iHS) methodology. Results A total of eight significant regions (P < 0.0001) of possible recent selection signatures were detected on BTA14 and BTA17. In addition, nine genes were identified in regions harboring selection signatures, such as KCNQ3, HHLA1, OC90, EFR3A, ADCY8, ASAP1, TMEM132B, and TMEM132C. Study of the reported QTLs in these regions of the bovine genome has showed that they are associated with important traits such as milk, reproduction and production traits. Conclusion The results revealed multiple genomic regions as well as multiple new genes under positive selection on BTA14 and BTA17. Moreover, candidate selected regions that overlap with QTL reported in the cattle QTL database provided additional evidence for the significance of the detected regions under selection. This study provides a foundation for detailed analysis of the identified putative selection signatures in the cattle genome particularly of the indigenous and locally-developed cattle breeds and provides an avenue for a well-structured breed improvement.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effects of methionine synthase and methionine synthase reductase polymorphisms on hypertension susceptibility
Genes & Genomics
2020 .01
-
Tuberculosis risk is associated with genetic polymorphisms in the LRP2, CUBN, and VDR genes
Genes & Genomics
2020 .01
-
Single Nucleotide Polymorphism Assay for Genetic Identification of Lophophora williamsii
한국분석과학회 학술대회
2020 .11
-
Strong Association of Regulatory Single Nucleotide Polymorphisms (SNPs) of the IFITM3 Gene with Influenza H1N1 2009 Pandemic Virus Infection
한국미생물학회 학술대회논문집
2020 .10
-
Association of COX2 −765G>C promoter polymorphism and coronary artery disease in Korean population
Genes & Genomics
2019 .01
-
Absence of Single Nucleotide Polymorphisms (SNPs) in the Open Reading Frame (ORF) of the Prion Protein Gene (PRNP) in a Large Sampling of Various Chicken Breeds
한국미생물학회 학술대회논문집
2020 .10
-
A Single Nucleotide Polymorphism in envZ Differentiates Virulence-related Phenotypes in Salmonella enterica serovar Enteritidis
한국미생물학회 학술대회논문집
2020 .10
-
Gender-specific association of polymorphisms in the 50-UTR and 30-UTR of VEGF gene with hypertensive patients
Genes & Genomics
2015 .01
-
Association study of the three functional polymorphisms (TAS2R46G>A, OR4C16G>A, and OR4X1A>T) with recurrent pregnancy loss
Genes & Genomics
2019 .01
-
Nucleotide-based Approach for the Development of β-Lactamase Inhibitors
한국미생물학회 학술대회논문집
2021 .08
-
Meta-analysis of the association between five single nucleotide polymorphisms in the BDNF gene and allergic inflammation susceptibility
Genes & Genomics
2017 .01
-
Associations of MTRR and TSER polymorphisms related to folate metabolism with susceptibility to metabolic syndrome
Genes & Genomics
2019 .01
-
Identification of Single Nucleotide Polymorphism Markers in the Laccase Gene of Shiitake Mushrooms (Lentinula edodes)
Mycobiology
2015 .01
-
단일염기다형성 정보를 이용한 국내 홀스타인 젖소의 유효집단 크기 추정
한국데이터정보과학회지
2017 .05
-
Association of glutathione S-transferase M1 and T1 null/present polymorphism with physical performance in the Korean population
Genes & Genomics
2019 .01
-
Associations of hypoxia inducible factor-1a gene polymorphisms with susceptibility to digestive tract cancers: a case–control study and meta-analysis
Genes & Genomics
2015 .01
-
Prognostic significance of three endothelial nitric oxide synthase (eNOS) polymorphisms and metabolic syndrome (MetS) in patients with colorectal cancer
Genes & Genomics
2022 .06
-
Sex-specific differences in the association of a common aldehyde dehydrogenase 2 gene polymorphism and alcohol consumption with stroke risk in a Korean population : a prospective cohort study
Nutrition Research and Practice
2015 .02
-
Sex-specific differences in the association of a common aldehyde dehydrogenase 2 gene polymorphism and alcohol consumption with stroke risk in a Korean population : a prospective cohort study
Nutrition Research and Practice
2015 .02
-
Association between Polymorphisms in Toll-like Receptor 9 Gene and Outcomes after Ischemic Stroke
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2015 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0