지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 672 - 677 (6page)
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초록· 키워드
오류제보하기
Background: Sarcopenia is defined as the loss of skeletal muscle mass and is associated with negative clinical outcomes. This study aimed to establish sex-specific cutoff values for the skeletal muscle area (SMA) and skeletal muscle index (SMI) at the third lumbar vertebral (L3) level using computed tomography (CT) imaging to identify sarcopenia in healthy Korean liver donors. Methods: This retrospective study included 659 healthy liver donors (408 men and 251 women) aged 20 to 60 years who had undergone abdominal CT examinations between January 2017 and December 2018. Assessment of body composition was performed with an automated segmentation technique using a deep-learning system. Sex-specific SMA and SMI distributions were assessed, and cutoff values for determining sarcopenia were defined as values at either two standard deviations (SDs) below the mean reference value or below the fifth percentile. Results: Using the SD definition, cutoff values for SMA and SMI were 117.04 cm2 and 39.33 cm2/m2, respectively, in men and 71.39 cm2 and 27.77 cm2/m2, respectively, in women. Using the fifth percentile definition, cutoff values for SMA and SMI were 126.88 cm2 and 40.96 cm2/m2, respectively, in men and 78.85 cm2 and 30.60 cm2/m2, respectively, in women. Conclusion: Our data provide sex-specific cutoff values for the SMA and SMI at the L3 level measured by CT imaging in a healthy Korean population, which may be applicable for identifying sarcopenia in this population.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Cruz-Jentoft AJ / 2010 / Sarcopenia : European consensus on definition and diagnosis : report of the European Working Group on Sarcopenia in Older People / Age Ageing 39:412~423
Chen LK / 2014 / Sarcopenia in Asia : consensus report of the Asian Working Group for Sarcopenia / J Am Med Dir Assoc 15:95~101
Cruz-Jentoft AJ / 2019 / Sarcopenia : revised European consensus on definition and diagnosis / Age Ageing 48:16~31
Walowski CO / 2020 / Reference values for skeletal muscle mass : current concepts and methodological considerations / Nutrients 12:755
Mourtzakis M / 2008 / A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care / Appl Physiol Nutr Metab 33:997~1006
Chen LK / 2014 / Sarcopenia in Asia : consensus report of the Asian Working Group for Sarcopenia / J Am Med Dir Assoc 15:95~101
Cruz-Jentoft AJ / 2019 / Sarcopenia : revised European consensus on definition and diagnosis / Age Ageing 48:16~31
Walowski CO / 2020 / Reference values for skeletal muscle mass : current concepts and methodological considerations / Nutrients 12:755
Mourtzakis M / 2008 / A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care / Appl Physiol Nutr Metab 33:997~1006
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