지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 250 - 259 (10page)
이용수
초록· 키워드
오류제보하기
Purpose: High-dose-rate brachytherapy (HDR-BT) with external beam radiation therapy (EBRT) is a common treatment option for locally advanced prostate cancer. Quality of life is an important factor when discussing therapy options for high-risk prostate cancer. This study evaluated adverse effects and health-related quality of life (HRQOL). Materials and Methods: Ninety male patients (median age, 71 years; range, 50 to 79 years) with high-risk prostate cancer underwent HDR-BT after EBRT between December 2009 and January 2017 with a median follow-up of 43 months. A total of 57 patients (69.5%) answered the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life of Cancer Patients questionnaire (QLQ-C30; ver. 3.0), and 8 patients died during follow-up. In order to put the results of this study in context, we compared the results with reference data from the EORTC QLQ-C30 Scoring Manual. Correlations of prostate-specific antigen (PSA) values, International Prostate Symptom Score, and HRQOL measures were calculated. Results: The study participants reported better physical functioning and better global health compared with the reference data, but worse social, role, and cognitive functioning. We found negative statistically significant correlations between the last-measured PSA value and social functioning (p>0.01), cognitive functioning, pain, and constipation (all p<0.05). Toxicity rates were 10.0% for gastrointestinal and 12.2% for genitourinary adverse effects. All reported complications for toxicity were Grade I. Conclusions: The described therapy results in high biochemical control rates with minimal adverse effects. Compared with reference groups, the HRQOL of this study cohort was acceptable. PSA values during follow-up seem to be a possible indicator to influence HRQOL.
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Heidenreich A / 2014 / EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent-update 2013 / Eur Urol 65:124~137
Sathya JR / 2005 / Randomized trial comparing iridium implant plus externalbeam radiation therapy with external-beam radiation therapy alone in node-negative locally advanced cancer of the prostate / J Clin Oncol 23:1192~1199
Hoskin PJ / 2012 / Randomised trial of external beam radiotherapy alone or combined with high-dose-rate brachytherapy boost for localised prostate cancer / Radiother Oncol 103:217~222
Mottet N / 2017 / EAU-ESTRO-SIOG guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent / Eur Urol 71:618~629
Lubeck DP / 1999 / Changes in health-related quality of life in the first year after treatment for prostate cancer : results from CaPSURE / Urology 53:180~186
Sathya JR / 2005 / Randomized trial comparing iridium implant plus externalbeam radiation therapy with external-beam radiation therapy alone in node-negative locally advanced cancer of the prostate / J Clin Oncol 23:1192~1199
Hoskin PJ / 2012 / Randomised trial of external beam radiotherapy alone or combined with high-dose-rate brachytherapy boost for localised prostate cancer / Radiother Oncol 103:217~222
Mottet N / 2017 / EAU-ESTRO-SIOG guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent / Eur Urol 71:618~629
Lubeck DP / 1999 / Changes in health-related quality of life in the first year after treatment for prostate cancer : results from CaPSURE / Urology 53:180~186
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
전립선의 염증반응과 전립선특이항원의 변화
Urogenital Tract Infection
2015 .01
-
Comparison of the Formula of PSA, Age, Prostate Volume and Race Versus PSA Density and the Detection of Primary Malignant Circulating Prostate Cells in Predicting a Positive Initial Prostate Biopsy in Chilean Men with Suspicion of Prostate Cancer
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Health-Related Quality of Life Changes in Prostate Cancer Patients after Radical Prostatectomy: A Longitudinal Cohort Study
Cancer Research and Treatment
2019 .01
-
Exponential Rise in Prostate-Specific Antigen (PSA) during Anti-Androgen Withdrawal Predicts PSA Flare after Docetaxel Chemotherapy in Patients with Castration-Resistant Prostate Cancer
Yonsei Medical Journal
2015 .01
-
Psychometric Validation of the Malaysian Chinese Version of the EORTC QLQ-C30 in Colorectal Cancer Patients
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Prostate Cancer Screening in the Fit Chilean Elderly: a Head to Head Comparison of Total Serum PSA versus Age Adjusted PSA versus Primary Circulating Prostate Cells to Detect Prostate Cancer at Initial Biopsy
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Afatinib 복약 후 발생한 비소세포성 폐암환자의 피부독성 부작용에 대한 한방치료 1례
대한한방내과학회지
2018 .01
-
Reliability and Validity of an Iranian Version of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for Patients with Multiple Myeloma: the EORTC QLQ-MY20
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Multicenter Comparison of Four Automated Immunoassay Analyzers for Prostate Specific Antigen
Annals of Laboratory Medicine
2019 .01
-
재발성 전립선암 환자에서 낮은 전립성특이항원을 보인폐전이 1예
대한내과학회지
2015 .01
-
Effect of training and individual operator's expertise on prostate cancer detection through prostate biopsy: Implications for the current quantitative training evaluation system
Investigative and Clinical Urology
2021 .11
-
Biomarkers for Evaluation of Prostate Cancer Prognosis
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
사회연결망분석을 적용한 암 환자의 건강 관련 삶의 질 연구
Asian Oncology Nursing
2020 .06
-
Predictors of Participation in Prostate Cancer Screening among Older Men in Jordan
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Advantages of Distal Subtotal Gastrectomy over Total Gastrectomy in the Quality of Life of Long-Term Gastric Cancer Survivors
Journal of Gastric Cancer
2020 .01
-
Hypofractionated intensity-modulated radiotherapy in patients with localized prostate cancer: a preliminary study
Radiation oncology journal : ROJ
2016 .01
-
Influence of repeated prostate-specific antigen screening on treatment pattern in a country with a limited social perception of prostate cancer: Korean national wide observational study
Investigative and Clinical Urology
2021 .01
-
Head to Head Comparison of the Chun Nomogram, Percentage Free PSA and Primary Circulating Prostate Cells to Predict the Presence of Prostate Cancer at Repeat Biopsy
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Impact of birth season on second-to-fourth digit ratio, prostate volume, and prostate cancer
Investigative and Clinical Urology
2022 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0