지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 107 - 118 (12page)
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초록· 키워드
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Background/Aims: Inflammatory bowel disease (IBD) is associated with considerable impairment of patients’ health-relatedquality of life (HRQoL). Knowledge of factors that significantly affect IBD patients’ HRQoL can contribute to better patient care. However, the HRQoL of IBD patients in non-Western countries are limited. Hence, we assessed the HRQoL of Singaporean IBDpatients and identified its determinants. Methods: A prospective, cross-sectional study was conducted at Singapore GeneralHospital outpatient IBD Centre. The HRQoL of IBD patients was assessed using the short IBD questionnaire (SIBDQ), ShortForm-36 physical and mental component summary (SF-36 PCS/MCS) and EuroQol 5-dimensions 3-levels (EQ-5D-3L) andvisual analogue scale (VAS). Independent samples t-test was used to compare HRQoL between Crohn’s disease (CD) and ulcerativecolitis (UC). Determinants of HRQoL were identified through multiple linear regression. Results: A total of 195 IBD patients(103 UC, 92 CD) with a mean disease duration of 11.2 years were included. There was no significant difference in HRQoLbetween patients with UC and CD. Factors that significantly worsened HRQoL were presence of active disease (b=−6.293[SIBDQ], −9.409 [PCS], −9.743 [MCS], −7.254 [VAS]), corticosteroids use (b=−7.392 [SIBDQ], −10.390 [PCS], −8.827 [MCS]), poormedication adherence (b=−4.049 [SIBDQ], −1.320 [MCS], −8.961 [VAS]), presence of extraintestinal manifestations (b=−13.381[PCS]), comorbidities (b=−4.531 [PCS]), non-employment (b=−9.738 [MCS], −0.104 [EQ-5D-3L]) and public housing (b=−8.070[PCS], −9.207 [VAS]). Conclusions: The HRQoL is impaired in this Asian cohort of IBD. The magnitude of HRQoL impairmentwas similar in UC and CD. Clinical characteristics were better determinants of patients’ HRQoL than socio-demographic factors. Recognizing the factors that impact patients’ HRQoL would improve the holistic management of IBD patients. (Intest Res2019;17:107-118)
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등록된 정보가 없습니다.
참고문헌 (53)
참고문헌 신청
Elson CO / 2012 / Host-microbiota interactions in inflammatory bowel disease / Gut Microbes 3:332~344
Ng SC / 2013 / Incidence and phenotype of inflammatory bowel disease based on results from the Asiapacific Crohn’s and colitis epidemiology study / Gastroenterology 145:158~165
Gan E / Bowel disease sufferers at higher risk of anxiety / TODAY Web site
Colìa R / 2016 / Rheumatologic and extraintestinal manifestations of inflammatory bowel diseases / Ann Med 48:577~585
Bernklev T / 2006 / Relationship between sick leave, unemployment, disability, and health-related quality of life in patients with inflammatory bowel disease / Inflamm Bowel Dis 12:402~412
Ng SC / 2013 / Incidence and phenotype of inflammatory bowel disease based on results from the Asiapacific Crohn’s and colitis epidemiology study / Gastroenterology 145:158~165
Gan E / Bowel disease sufferers at higher risk of anxiety / TODAY Web site
Colìa R / 2016 / Rheumatologic and extraintestinal manifestations of inflammatory bowel diseases / Ann Med 48:577~585
Bernklev T / 2006 / Relationship between sick leave, unemployment, disability, and health-related quality of life in patients with inflammatory bowel disease / Inflamm Bowel Dis 12:402~412
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