지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 244 - 249 (6page)
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초록· 키워드
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Objectives: We aim to elucidate the clinical outcomes of bisphosphonate-associated atypical femoral fracture and the clinical results depending on the bisphosphonate therapy period. Methods: Twenty cases involving 15 patients who had been diagnosed with atypical femoral facture between 2004 and 2014 and who had been followed up for at least 12 months were retrospectively analyzed. The control group was composed of 15 typical femoral facture patients. We used plain radiography and physical examinations to determine the period of time required for fracture healing as well as complication occurrence. We investigated the bisphosphonate administration status and duration and the names of its components, bilateral fracture occurrence status, the period of time required for bone union, and reoperation or bone graft status due to nonunion. Results: Revision surgery involving a bone graft was performed due to nonunion in 1 out of 15 cases. Except in one revision case, the duration of the union was 11.9 months on average in 14 cases of atypical fracture patients, and 4.3 months on average in the control group. This difference was statistically significant (p < 0.05). The bisphosphonate administration duration was positively correlated with the union period (p < 0.05). In contrast, there was no statistically significant correlation between the bisphosphonate administration duration and the incidence of bilateral atypical fractures (p > 0.05). Conclusions: Atypical femoral fractures required more time for bone union than typical ones and prolonged bisphosphonate administration led to a longer period of time required for bone union.
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등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
이영균 / 2013 / 비전형적 대퇴골 골절의 역학 및 임상적 특성 / 대한정형외과학회지 48(3):175~179
Neviaser AS / 2008 / Lowenergy femoral shaft fractures associated with alendronate use / J Orthop Trauma 22(5):346~350
Lenart BA / 2009 / Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study / Osteoporos Int 20(8):1353~1362
Schneider JP / 2006 / Should bisphosphonates be continued indefinitely? An unusual fracture in a healthy woman on long-term alendronate / Geriatrics 61(1):31~33
Shane E / 2010 / American Society for bone and mineral research. Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for bone and mineral research / J Bone Min Res 25(11):2267~2294
Neviaser AS / 2008 / Lowenergy femoral shaft fractures associated with alendronate use / J Orthop Trauma 22(5):346~350
Lenart BA / 2009 / Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study / Osteoporos Int 20(8):1353~1362
Schneider JP / 2006 / Should bisphosphonates be continued indefinitely? An unusual fracture in a healthy woman on long-term alendronate / Geriatrics 61(1):31~33
Shane E / 2010 / American Society for bone and mineral research. Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for bone and mineral research / J Bone Min Res 25(11):2267~2294
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