지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 122 - 130 (9page)
이용수
초록· 키워드
오류제보하기
Objective. Productivity loss was compared by 3-stage of disease activity and associations between higher disease activity and high productivity loss were identified. Methods. Data were extracted from Rheumatoid Arthritis (RA) Patient-reported Outcomes Research, which enrolled 2,000 RA patients (＞20-year) on disease-modifying-antirheumatic-drugs (DMARDs) (≥6-month) from December 2012 to June 2013. This included 1,457 RA patients with the disease activity score (DAS-28-ESR) in their medical charts. Productivity loss in time and indirect cost was estimated using The World Health Organization Health and Work Performance Questionnaire (HPQ). Baseline characteristics and productivity loss outcomes were compared according to DAS-28-ESR groups. Results. 84.4% were females, 54.2% had low DAS-28-ESR (＜3.2), and 38.2% and 7.6% had moderate (3.2∼5.1) and high DAS-28-ESR (＞5.1). Patients with moderate to high DAS-28-ESR had higher lost productivity time (LPT) and monthly costs of LPT than those with low DAS-28-ESR (time in hours: 110.0±58.4 vs. 132.4±57.2 vs. 71.5±52.0, p＜0.0001; monthly costs of LPT in 1,000 Korean won: 1,097±607 vs. 1,302±554 vs. 741±531, p＜0.0001). Multiple regression analyses revealed significant associations with high LPT in high (adjusted odds ratio [OR]=3.87, 95% confidence interval [CI]: 2.18∼6.87) and moderate DAS-28-ESR (adjusted OR=1.88, 95% CI: 1.41∼2.52) compared to low DAS-28-ESR. In addition, positive associations with high monthly costs of LPT were observed in high (adjusted OR=3.45, 95% CI: 1.98∼5.99) and moderate DAS-28-ESR (adjusted OR=1.93, 95% CI: 1.43∼2.54) compared to low DAS-28-ESR. Conclusion. Timely therapeutic strategies should be taken into consideration given that the RA patients with moderate to high DAS-28-ESR showed strong associations with high productivity loss for effective management of RA.
목차
등록된 정보가 없습니다.
참고문헌 (37)
참고문헌 신청
Filipovic I / 2011 / Quantifying the economic burden of productivity loss in rheumatoid arthritis / Rheumatology (Oxford) 50:1083~1090
Pisetsky DS / 2001 / Progress in the treatment of rheumatoid arthritis / JAMA 286:2787~2790
Bardwell WA / 2002 / Rheumatoid arthritis severity scale: a brief, physician-completed scale not confounded by patient self-report of psychological functioning / Rheumatology (Oxford) 41:38~45
Fransen J / 2009 / The disease activity score and the EULAR response criteria / Rheum Dis Clin North Am 35:745~757
van der Heijde DM / 1992 / Validity of single variables and composite indices for measuring disease activity in rheumatoid arthritis / Ann Rheum Dis 51:177~181
Pisetsky DS / 2001 / Progress in the treatment of rheumatoid arthritis / JAMA 286:2787~2790
Bardwell WA / 2002 / Rheumatoid arthritis severity scale: a brief, physician-completed scale not confounded by patient self-report of psychological functioning / Rheumatology (Oxford) 41:38~45
Fransen J / 2009 / The disease activity score and the EULAR response criteria / Rheum Dis Clin North Am 35:745~757
van der Heijde DM / 1992 / Validity of single variables and composite indices for measuring disease activity in rheumatoid arthritis / Ann Rheum Dis 51:177~181
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Comparison of Disease Activity Score 28 Using C-reactive Protein and Disease Activity Score 28 Using Erythrocyte Sedimentation Rate in Assessing Activity and Treatment Response in Rheumatoid Arthritis: A Meta-analysis
대한류마티스학회지
2016 .01
-
Upregulation of ESR1 Gene and ESR Ratio(ESR1/ESR2) are Associated with Worse Prognosis in Papillary Thyroid Carcinoma
대한외과학회 학술대회 초록집
2016 .11
-
Elevated Erythrocyte Sedimentation Rate Is Predictive of Interstitial Lung Disease and Mortality in Dermatomyositis: a Korean Retrospective Cohort Study
Journal of Korean Medical Science
2016 .01
-
Treat-to-Target Strategy for Asian Patients with Early Rheumatoid Arthritis: Result of a Multicenter Trial in Korea
Journal of Korean Medical Science
2018 .01
-
Clinical and immunological responses to COVID-19 vaccination in rheumatoid arthritis patients on disease modifying antirheumatic drugs: a cross-sectional study
대한류마티스학회지
2024 .01
-
Korean Red Ginseng exhibits no significant adverse effect on disease activity in patients with rheumatoid arthritis : a randomized, double-blind, crossover study
Journal of Ginseng Research
2018 .04
-
Effects of romosozumab or denosumab treatment on the bone mineral density and disease activity for 6 months in patients with rheumatoid arthritis with severe osteoporosis: An open-label, randomized, pilot study
Osteoporosis and Sarcopenia
2021 .09
-
Treatment of Spinal Epidural Abscess and Predisposing Factors of Motor Weakness: Experience with 48 Patients
Neurospine
2015 .01
-
C-reactive Protein and Erythrocyte Sedimentation Rate Discrepancies and Variations after Intravenous Immunoglobulin Therapy in Kawasaki Disease
Pediatric Infection and Vaccine
2016 .01
-
The Impact of the Amendment of the Korean National Health Insurance Reimbursement Criteria for Anti-tumor Necrosis Factor- Agents on Treatment Pattern, Clinical Response and Persistence in Patients With Rheumatoid Arthritis
대한류마티스학회지
2020 .01
-
Wheel Balanced Cancer Therapy for Longer Than 21 Days Can Have a Positive Effect on the Survival of Patients with Stage IV Cancer
Journal of Pharmacopuncture
2015 .01
-
Letter to the Editor: Commentary on Spinal Surgery and Subsequent ESR and WBC Changes Pattern: A Single Center Prospective Study (Korean J Neurotrauma?2021;17:136?147)
Korean Journal of Neurotrauma
2021 .10
-
Circulating leptin and its correlation with rheumatoid arthritis activity: a meta-analysis
대한류마티스학회지
2023 .04
-
Evaluation of Serum Matrix Metalloproteinase-3 as an Objective Indicator for the Disease Activity in Rheumatoid Arthritis Patients Treated With Methotrexate Versus Tocilizumab: 24-week Results From a Prospective Randomized Controlled Study
대한류마티스학회지
2022 .04
-
YKL-40 Levels in Rheumatoid Arthritis and Their Correlation with Disease Activity: A Meta-analysis
대한류마티스학회지
2019 .01
-
Letter to the Editor: Commentary on Recurrent Cervical Spontaneous Spinal Epidural Hematoma with Conservative Management: A Case Report (Korean J Neurotrauma?2021;17:186?191)
Korean Journal of Neurotrauma
2021 .10
-
Effectiveness and Safety of Tacrolimus in Patients with Active Rheumatoid Arthritis with Inadequate Response to Disease-modifying Anti-rheumatic Drugs: The TREASURE Study
대한류마티스학회지
2019 .01
-
한국형 치매 시뮬레이션 프로그램의 효과 : 예비 연구
노인정신의학
2019 .01
-
Periodontal pathogens and the association between periodontitis and rheumatoid arthritis in Korean adults
Journal of Periodontal & Implant Science
2018 .01
-
Spinal Surgery and Subsequent ESR and WBC Changes Pattern: A Single Center Prospective Study
Korean Journal of Neurotrauma
2021 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0