지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 529 - 538 (10page)
이용수
초록· 키워드
오류제보하기
Marbling is a crucial characteristic in meat quality assessment. In the search for a genetic basis of meat quality, a large number of gene analyses seeking to find loci for a marbling trait have already been reported. However, the influence of microRNA (miRNA) on expression patterns and their ultimate influence on marbling is poorly understood. To better understand posttranscriptional influences on marbling, we applied a microarray analysis to measure the relationship between marbling scores and miRNA and messenger RNA expression in Hanwoo longissimus muscle tissue. Our results build correlations between miRNAs and differentially expressed genes and pathways. Our microarray analysis identified 763 genes and 11 miRNAs that are differentially expressed relative to marbling score. Overall, upregulated miRNAs were associated with downregulated genes. Fifteen genes targeted by miRNAs including insulin-like growth factor 1 (IGF-1) and kruppel-like factor 11 (KLF11), which regulate fatty acid synthase and lipid metabolism. And the expression levels of KLF11 and btamiR- 494 were validated. The results show that downregulated bta-miR-494 was associated with the upregulation of KLF11 gene. Among the differentially expressed genes found to be associated with the marbling score, we identified 15 genes targeted by miRNAs. Furthermore, the expression patterns of the genes KLF11, and bta-miR-494, may influence marbling in Hanwoo.
목차
등록된 정보가 없습니다.
참고문헌 (33)
참고문헌 신청
Avile´s C / 2013 / Associations between DGAT1, FABP4, LEP, RORC, and SCD1 gene polymorphisms and fat deposition in Spanish commercial beef / J Anim Sci 91:4571~4577
Bartel DP / 2004 / microRNAs: genomics, biogenesis, mechanism, and function / Cell 116:281~297
Bartel DP / 2009 / microRNAs: target recognition and regulatory functions / Cell 136:215~233
Bolstad BF / 2005 / Quality assessment of Affymetrix GeneChip data / Springer :33~47
Bong JJ / 2012 / Differential expression of genes associated with lipid metabolism in longissimus dorsi of Korean bulls and steers / Meat Sci 91:284~293
Bartel DP / 2004 / microRNAs: genomics, biogenesis, mechanism, and function / Cell 116:281~297
Bartel DP / 2009 / microRNAs: target recognition and regulatory functions / Cell 136:215~233
Bolstad BF / 2005 / Quality assessment of Affymetrix GeneChip data / Springer :33~47
Bong JJ / 2012 / Differential expression of genes associated with lipid metabolism in longissimus dorsi of Korean bulls and steers / Meat Sci 91:284~293
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Genetic features of Haliotis discus hannai by infection of vibrio and virus
Genes & Genomics
2020 .01
-
Identification of MicroRNAs as potential biomarkers for detecting ischemic stroke
Genes & Genomics
2022 .01
-
Genome-wide identification of drought-responsive microRNAs and their target genes in Chinese jujube by deep sequencing
Genes & Genomics
2023 .02
-
In Silico Study of miRNA Based Gene Regulation, Involved in Solid Cancer, by the Assistance of Argonaute Protein
Genomics & informatics
2016 .01
-
High throughput sequencing of herbaceous peony small RNAs to screen thermo-tolerance related microRNAs
Genes & Genomics
2017 .01
-
Identification and comparative analysis of the pearl oyster Pinctada fucata hemocytes microRNAs in response to Vibrio alginolyticus infection
Genes & Genomics
2017 .01
-
Disease-miRNAdb: a manually-curated database for the investigation of the microRNA-human disease relationship
Genes & Genomics
2017 .01
-
Determinants of Functional MicroRNA Targeting
Molecules and Cells
2023 .01
-
Characterization and differential expression of microRNA in skeletal muscle of Laiwu and Yorkshire pig breeds
Genes & Genomics
2017 .01
-
Deep sequencing reveals microRNA signature is altered in the rat epididymis following bilateral castration
Genes & Genomics
2019 .01
-
Genome-wide identification, characterisation and expression profile analysis of DEAD-box family genes in sweet potato wild ancestor Ipomoea trifida under abiotic stresses
Genes & Genomics
2020 .01
-
The SnRK2 family in pepper (Capsicum annuum L.): genome-wide identifcation and expression analyses during fruit development and under abiotic stress
Genes & Genomics
2020 .01
-
Discovery and profiling of microRNAs and their targets in Paulownia ‘Yuza 1’ plants via high-throughput sequencing and degradome analysis
Genes & Genomics
2016 .01
-
Genomic identification of microRNA promoters and their cis-acting elements in Populus
Genes & Genomics
2016 .01
-
Identification and differential expression of microRNAs in Madin–Darby canine kidney cells with high and low tumorigenicities
Genes & Genomics
2022 .02
-
Identification of differentially expressed miRNAs after Lactobacillus reuteri treatment in the ileum mucosa of piglets
Genes & Genomics
2020 .01
-
Circulating microRNA expression profiling in young obese Korean women
Nutrition Research and Practice
2020 .08
-
Physiological responses and small RNAs changes in maize under nitrogen deficiency and resupply
Genes & Genomics
2019 .01
-
MicroRNA Target Recognition: Insights from Transcriptome-Wide Non-Canonical Interactions
Molecules and Cells
2016 .05
-
Circulating microRNA expression profiling in young obese Korean women
Nutrition Research and Practice
2020 .08
이 논문의 저자 정보
최근 본 자료
댓글(0)
0