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논문 기본 정보

자료유형
학술저널
저자정보
Youran Gao (Department of Gastroenterology and Hepatology Hofstra Northwell School of Medicine) Sundas Khan (Department of Internal Medicine Northwell Health Systems Hofstra Northwell School of Medicine) Meredith Akerman (Feinstein Institute for Medical Research Biostatistics Unit) Keith Sultan (Department of Gastroenterology and Hepatology Hofstra Northwell School of Medicine)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.15 No.1
발행연도
2017.1
수록면
83 - 89 (7page)

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Background/Aims: Opiate use for inflammatory bowel disease (IBD), particularly high-dose (HD) use, is associated withincreased mortality. It’s assumed that opiate use is directly related to IBD-related complaints, although this hasn’t been welldefined. Our goal was to determine the indications for opiate use as a first step in developing strategies to prevent or decreaseopiate use. Methods: A retrospective cohort was formed of adults who were diagnosed with IBD and for whom outpatientevaluations from 2009 to 2014 were documented. Opiate use was defined if opiates were prescribed for a minimum of 30 daysover a 365-day period. Individual chart notes were then reviewed to determine the clinical indication(s) for low-dose (LD) andHD opiate use. Results: After a search of the electronic records of 1,109,277 patients, 3,226 patients with IBD were found. Onehundred four patients were identified as opiate users, including 65 patients with Crohn’s and 39 with ulcerative colitis; a totalof 134 indications were available for these patients. IBD-related complaints accounted for 49.25% of the opiate indications,with abdominal pain (23.13%) being the most common. Overall, opiate use for IBD-related complaints (81.40% vs. 50.82%;P =0.0014) and abdominal pain (44.19% vs. 19.67%; P =0.0071) was more common among HD than among LD. Conclusions:Our findings show that most IBD patients using opiates, particularly HD users, used opiates for IBD-related complaints. Futureresearch will need to determine the degree to which these complaints are related to disease activity and to formulate nonopiatepain management strategies for patients with both active and inactive IBD.

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