지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Fecal microbiota transplantation is a technique for treating patients suffering from Clostridium difficile infection who do not positively respond to traditional treatment with antibiotics or whose infections have recurred, by transplanting the feces of healthy individuals. The objective of this review is to evaluate the safety and effectiveness of fecal microbiota transplantation. A literature search was conducted using 8 Korean databases, Medline, Embase, and the Cochrane Library. Of the 1,410 articles that were initially identified, 30 studies were included in this review. The results show that the incidence of major complications was low and that mild complications resolved. Improvements in the symptoms of diarrhea after treatment were observed and the rate of recurrence was acceptable. On the basis of the current data, fecal microbiota transplantation can be considered a safe and effective technique for treating patients suffering from C. difficile infection who do not positively respond to traditional treatment with antibiotics or whose infections have recurred.
목차
등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
McDonald LC / 2006 / Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003 / Emerg Infect Dis 12:409~415
Gilca R / 2010 / Epidemiological patterns and hospital characteristics associated with increased incidence of Clos-tridium difficile infection in Quebec, Canada, 1998-2006 / Infect Control Hosp Epidemiol 31:939~947
Pepin J / 2004 / Clostridium difficileassociated diarrhea in a region of Quebec from 1991 to 2003:a changing pattern of disease severity / CMAJ 171:466~472
McFarland LV / 2002 / Breaking the cycle:treatment strategies for 163 cases of recurrent Clostridium difficile disease / Am J Gastroenterol 97:1769~1775
Kelly CP / 2008 / Clostridium difficile: more difficult than ever / N Engl J Med 359:1932~1940
Gilca R / 2010 / Epidemiological patterns and hospital characteristics associated with increased incidence of Clos-tridium difficile infection in Quebec, Canada, 1998-2006 / Infect Control Hosp Epidemiol 31:939~947
Pepin J / 2004 / Clostridium difficileassociated diarrhea in a region of Quebec from 1991 to 2003:a changing pattern of disease severity / CMAJ 171:466~472
McFarland LV / 2002 / Breaking the cycle:treatment strategies for 163 cases of recurrent Clostridium difficile disease / Am J Gastroenterol 97:1769~1775
Kelly CP / 2008 / Clostridium difficile: more difficult than ever / N Engl J Med 359:1932~1940
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