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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 31 - 39 (9page)
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Diets with high fiber content improve most metabolic syndrome (MetS) profile in nondiabetic individuals, but there is scarce information about the role of fiber intake in patients with the MetS and diabetes. The objective of this study is to determine whether soluble fiber supplementation improve MetS profile for 8 weeks of intervention in newly diagnosed type 2 diabetes (T2D) adult patients. After one week of dietary stabilization phase, 36 newly diagnosed T2D patients were stratified to different strata according to sex, age, fasting blood sugar (FBS), and waist circumference (WC). Then they were randomly allocated into 2 groups. The psyllium group (n = 18) received 10.5 g of psyllium daily for 8 weeks. The control group (n = 18) maintained their regular diet for 8 weeks. Soluble fiber supplementation showed significant reduction in the majority of MetS profile; FBS (43.55 mg/dL, p < 0.001), triglyceride (37.89 mg/dL, p < 0.001), total cholesterol (20.32 mg/dL, p < 0.001), systolic blood pressure (7.50 mmHg, p < 0.001), diastolic blood pressure (2.78 mmHg, p = 0.013), and WC (2.54 cm, p < 0.001) in the intervention group compared with the control group after 8 weeks of intervention. The high-density lipoprotein cholesterol was reduced in both groups, but this reduction was insignificant. The improvement in the MetS profile was enhanced by combining psyllium to the normal diet. Consumption of foods containing moderate amounts of these fibers may improve MetS profile in newly diagnosed T2D patients. This study was registered in Current Controlled Trials (PHRC/HC/28/15).
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참고문헌 (46)
참고문헌 신청
Expert Panel on Detection / 2001 / Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) / JAMA 285:2486~2497
Grundy SM / 2005 / Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement / Circulation 112:2735~2752
Miranda PJ / 2005 / Metabolic syndrome: definition, pathophysiology, and mechanisms / Am Heart J 149:33~45
Sliem HA / 2012 / Metabolic syndrome in the Middle East / Indian J Endocrinol Metab 16:67~71
Abutair AS / 2016 / Soluble fibers from psyllium improve glycemic response and body weight among diabetes type 2 patients (randomized control trial) / Nutr J 15:86
Grundy SM / 2005 / Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement / Circulation 112:2735~2752
Miranda PJ / 2005 / Metabolic syndrome: definition, pathophysiology, and mechanisms / Am Heart J 149:33~45
Sliem HA / 2012 / Metabolic syndrome in the Middle East / Indian J Endocrinol Metab 16:67~71
Abutair AS / 2016 / Soluble fibers from psyllium improve glycemic response and body weight among diabetes type 2 patients (randomized control trial) / Nutr J 15:86
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