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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 673 - 679 (7page)
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초록· 키워드
오류제보하기
After the approval and introduction of mirabegron, tadalafil, and botulinum toxin A for treatment of lower urinary tract symptoms/overactive bladder, focus of interest has been on their place in therapy versus the previous gold standard, antimuscarinics. However, since these agents also have limitations there has been increasing interest in what is coming next - what is in the pipeline? Despite progress in our knowledge of different factors involved in both peripheral and central modulation of lower urinary tract dysfunction, there are few innovations in the pipe-line. Most developments concern modifications of existing principles (antimuscarinics, β3-receptor agonists, botulinum toxin A). However, there are several new and old targets/drugs of potential interest for further development, such as the purinergic and cannabinoid systems and the different members of the transient receptor potential channel family. However, even if there seems to be good rationale for further development of these principles, further exploration of their involvement in lower urinary tract function/dysfunction is necessary.
목차
등록된 정보가 없습니다.
참고문헌 (74)
참고문헌 신청
Andersson KE / 2013 / Selective β3-adrenoceptor agonists for the treatment of overactive bladder / J Urol 190:1173~1180
Chapple CR / 2014 / Mirabegron in overactive bladder: a review of efficacy, safety, and tolerability / Neurourol Urodyn 33:17~30
Mangera A / 2014 / An updated systematic review and statistical comparison of standardised mean outcomes for the use of botulinum toxin in the management of lower urinary tract disorders / Eur Urol 65:981~990
Lythgoe C / 2013 / The use of PDE-5 inhibitors in the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia / Curr Urol Rep 14:585~594
Yeo EK / 2013 / New therapies in the treatment of overactive bladder / Expert Opin Emerg Drugs 18:319~337
Chapple CR / 2014 / Mirabegron in overactive bladder: a review of efficacy, safety, and tolerability / Neurourol Urodyn 33:17~30
Mangera A / 2014 / An updated systematic review and statistical comparison of standardised mean outcomes for the use of botulinum toxin in the management of lower urinary tract disorders / Eur Urol 65:981~990
Lythgoe C / 2013 / The use of PDE-5 inhibitors in the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia / Curr Urol Rep 14:585~594
Yeo EK / 2013 / New therapies in the treatment of overactive bladder / Expert Opin Emerg Drugs 18:319~337
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