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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 146 - 153 (8page)
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Background: Psychosocial stress has been hypothesized to impact renal changes, but this hypothesis has not been adequately tested. The aim of this study was to examine the relationship between psychosocial stress and estimated glomerular filtration rate (eGFR) and to examine other predictors of eGFR changes among persons with diabetes mellitus (DM). Methods: Data from a survey conducted in 2005 by a major health maintenance organization located in the southeastern part of the United States, linked to patients’ clinical and pharmacy records (n¼575) from 2005 to 2008, was used. Study participants were working adults aged 25–59 years, diagnosed with DM but without advanced microvascular or macrovascular complications. eGFR was estimated using the Modification of Diet in Renal Disease equation. A latent psychosocial stress variable was created from five psychosocial stress subscales. Using a growth factor model in a structural equation framework, we estimated the association between psychosocial stress and eGFR while controlling for important covariates. Results: The psychosocial stress variable was not directly associated with eGFR in the final model. Factors found to be associated with changes in eGFR were age, race, insulin use, and mean arterial pressure. Conclusion: Among fairly healthy DM patients, we did not find any evidence of a direct association between psychosocial stress and eGFR changes after controlling for important covariates. Predictors of eGFR change in our population included age, race, insulin use, and mean arterial pressure.
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등록된 정보가 없습니다.
참고문헌 (65)
참고문헌 신청
Jerums G / 2009 / Integrating albuminuria and GFR in the assessment of diabetic nephropathy / Nat Rev Nephrol 5:397~406
Tseng CH / 2004 / Mortality and causes of death in a national sample of diabetic patients in Taiwan / Diabetes Care 27:1605~1609
Orchard TJ / 2010 / In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population : a report from the Pittsburgh Epidemiology of Diabetes Complications Study / Diabetologia 53:2312~2319
Tervaert TW / 2010 / Renal Pathology Society : Pathologic classification of diabetic nephropathy / J Am Soc Nephrol 21:556~563
Powell DW / 2013 / Associations between structural and functional changes to the kidney in diabetic humans and mice / Life Sci 93:257~264
Tseng CH / 2004 / Mortality and causes of death in a national sample of diabetic patients in Taiwan / Diabetes Care 27:1605~1609
Orchard TJ / 2010 / In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population : a report from the Pittsburgh Epidemiology of Diabetes Complications Study / Diabetologia 53:2312~2319
Tervaert TW / 2010 / Renal Pathology Society : Pathologic classification of diabetic nephropathy / J Am Soc Nephrol 21:556~563
Powell DW / 2013 / Associations between structural and functional changes to the kidney in diabetic humans and mice / Life Sci 93:257~264
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