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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Purpose: The relationship between prognostic factors and outcomes of post-cardiac arrest patients treated with therapeutic hypothermia was analyzed. Methods: We conducted a tertiary center retrospective study of post-cardiac arrest patients treated with therapeutic hypothermia between January 2008 and December 2012. We investigated the association of the following factors with outcomes: BMI, time to ROSC, number of vasoactive drugs, smoking, alcohol, and short time to therapeutic range in hypothermia. Results: A total of 251 patients were enrolled in this study. Large number of vasoactive drugs was a prognostic factor of 3-month mortality (adjusted OR 1.96, 95% CI:1.41-2.71, p<0.001). Obesity (BMI≥25 kg/m2) was not associated with delayed time to therapeutic range in hypothermia. Both univariate and multivariate analysis showed that high initial BT (β(SE)=63.64 (11.53), p<0.001) and a small number of vasoactive drugs (β(SE)=18.66(8.74), p=0.034) were independent predictors of delayed time to therapeutic range in hypothermia. Conclusion: In this study, a small number of vasoactive drugs showed a significant influence on delayed time to therapeutic range in patients receiving therapeutic hypothermia after return of spontaneous circulation after out-of-hospital cardiac arrest.
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참고문헌 (24)
참고문헌 신청
http://cdc.go.kr/CDC/info/ CdcKrInfo0301. jsp?menuIds=HOME001-MNU1154-MNU0005-MNU0037&q_type=&year=2012&cid=18352&pageNum=
Peberdy MA / 2010 / Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care / Circulation 122:S768~S786
Flint AC / 2007 / Therapeutic hypothermia after cardiac arrest : performance characteristics and safety of surface cooling with or without endovascular cooling / Neurocrit Care 7:109~118
Pichon N / 2007 / Efficacy of and tolerance to mild induced hypothermia after out-of-hospital cardiac arrest using an endovascular cooling system / Crit Care 11:R71
Haugh M / 2011 / Relationship between time to target temperature and outcome in patients treated with therapeutic hypothermia after cardiac arrest / Crit Care 15:R101
Peberdy MA / 2010 / Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care / Circulation 122:S768~S786
Flint AC / 2007 / Therapeutic hypothermia after cardiac arrest : performance characteristics and safety of surface cooling with or without endovascular cooling / Neurocrit Care 7:109~118
Pichon N / 2007 / Efficacy of and tolerance to mild induced hypothermia after out-of-hospital cardiac arrest using an endovascular cooling system / Crit Care 11:R71
Haugh M / 2011 / Relationship between time to target temperature and outcome in patients treated with therapeutic hypothermia after cardiac arrest / Crit Care 15:R101
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