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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.1
- 수록면
- 23 - 32 (10page)
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초록· 키워드
오류제보하기
Panax polysaccharides are biopolymers that are isolated and purified from the roots, stems, leaves, flowers, and fruits of Panax L. plants, which have attracted considerable attention because of their immunomodulatory activities. In this paper, the composition and structural characteristics of purified polysaccharides are reviewed. Moreover, the immunomodulatory activities of polysaccharides are described both in vivo and in vitro. In vitro, Panax polysaccharides exert immunomodulatory functions mainly by activating macrophages, dendritic cells, and the complement system. In vivo, Panax polysaccharides can increase the immune organ indices and stimulate lymphocytes. In addition, this paper also discusses the membrane receptors and various signalling pathways of immune cells. Panax polysaccharides have many beneficial therapeutic effects, including enhancing or activating the immune response, and may be helpful in treating cancer, sepsis, osteoporosis, and other conditions. Panax polysaccharides have the potential for use in the development of novel therapeutic agents or adjuvants with beneficial immunomodulatory properties.
목차
ABSTRACT
1. Introduction
2. Composition and structural characterisation
3. Immunomodulatory activity of Panax polysaccharides in vitro
4. Immunomodulatory activity of Panax polysaccharides in vivo
5. Immunomodulatory in intestine of Panax polysaccharides
6. Therapeutic potential of Panax polysaccharides
7. Conclusion
References
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UCI(KEPA) : I410-ECN-0101-2022-524-001132577