지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.1
- 수록면
- 37 - 44 (8page)
이용수
초록· 키워드
오류제보하기
Objectives: Tic disorders are highly heritable; however, growing evidence suggests that environmental factors play a significant role in their pathogenesis. Studies on these factors have been inconsistent, with conflicting results. Therefore, this study aimed to examine the associations of pre- and perinatal exposure to Tourette syndrome (TS) or chronic tic disorders (CTD) in Korean school-aged children.
Methods: This case-control study used data from a large prospective cohort study. The primary outcome was TS/CTD diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria and Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean Version. Demographic, pre-, and perinatal information was obtained from the maternal questionnaires. Data between the TS/CTD and control groups were compared using the chi-squared or Student’s t-test, as appropriate. Two-step logistic regression analyses were used to test the association between TS/CTD and pre- and perinatal risk factors.
Results: We included of 223 children (78 with TS/CTD and 145 controls). Significant differences in the demographic data between the two groups were observed. The male sex ratio, mean parental age, parental final education level, and family history of tics were included as confounders. In the final adjusted multivariable model, TS/CTD was significantly associated with antiemetic exposure during pregnancy (odds ratio [OR]=16.61, 95% confidence interval [CI] 1.49–185.22, p=0.02) and medically assisted reproduction (OR=7.89, 95% CI 2.28–27.28, p=0.01).
Conclusion: Antiemetic exposure and medically assisted reproduction are significantly associated with the risk of TS/CTD. These results should be replicated in future prospective and gene-by-environment studies.
Methods: This case-control study used data from a large prospective cohort study. The primary outcome was TS/CTD diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria and Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean Version. Demographic, pre-, and perinatal information was obtained from the maternal questionnaires. Data between the TS/CTD and control groups were compared using the chi-squared or Student’s t-test, as appropriate. Two-step logistic regression analyses were used to test the association between TS/CTD and pre- and perinatal risk factors.
Results: We included of 223 children (78 with TS/CTD and 145 controls). Significant differences in the demographic data between the two groups were observed. The male sex ratio, mean parental age, parental final education level, and family history of tics were included as confounders. In the final adjusted multivariable model, TS/CTD was significantly associated with antiemetic exposure during pregnancy (odds ratio [OR]=16.61, 95% confidence interval [CI] 1.49–185.22, p=0.02) and medically assisted reproduction (OR=7.89, 95% CI 2.28–27.28, p=0.01).
Conclusion: Antiemetic exposure and medically assisted reproduction are significantly associated with the risk of TS/CTD. These results should be replicated in future prospective and gene-by-environment studies.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Pathological interpretation of connective tissue disease-associated lung diseases
Journal of Yeungnam Medical Science
2019 .01
-
Beliefs about Tic Disorders and Tourette’s Syndrome in South Korea: An Online Panel Survey
소아청소년정신의학
2019 .07
-
Relationship Among Tic Symptoms, Expressed Emotion and Quality of Life in Children and Adolescents Patients with Tic Disorder
대한소아청소년정신의학회 학술대회논문집
2018 .11
-
A Review of Cognitive and Behavioral Interventions for Tic Disorder
소아청소년정신의학
2021 .04
-
Pathological interpretation of connective tissue disease-associated lung diseases
영남의대학술지
2019 .01
-
The Clinical Characterization of Blocking Tics in Patients With Tourette Syndrome
Journal Of Movement Disorders
2023 .05
-
Costunolide suppresses colorectal cancer proliferation and induces apoptosis in vitro and in vivo via targeting AKT independent on p53
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Effects of Group Comprehensive Behavioral Intervention for Tics in Children With Tourette’s Disorder and Chronic Tic Disorder
소아청소년정신의학
2022 .10
-
국내외 설진기를 활용한 인간 대상 연구현황
대한한의진단학회지
2015 .01
-
Structural differences in deep brain structures in pediatric tic patients
대한소아청소년정신의학회 학술대회논문집
2023 .11
-
Epigenome-wide Association Study for Tic Disorders in Children: A Preliminary Study in Korean Population
Clinical Psychopharmacology and Neuroscience
2024 .05
-
Diagnostic Hierarchy of Tic Disorders in Real-World Clinical Practice
소아청소년정신의학
2023 .10
-
Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 5. Connective Tissue Disease Associated Interstitial Lung Disease
Tuberculosis and Respiratory Diseases
2019 .01
-
A Single Case of Tourette’s Syndrome Treated with Traditional Chinese Medicine
Journal of Acupuncture & Meridian Studies
2017 .01
-
Study on Resting-State Functional Connectivity in Tic Disorder Patients
대한소아청소년정신의학회 학술대회논문집
2023 .11
-
Augmentation Index in Connective Tissue Diseases
대한류마티스학회지
2017 .01
-
틱장애 침치료에 대한 체계적 문헌고찰
대한한방소아과학회지
2017 .01
-
Chasing Tics in the Human Brain: Development of Open, Scheduled and Closed Loop Responsive Approaches to Deep Brain Stimulation for Tourette Syndrome
Journal of Clinical Neurology
2015 .01
-
Epigenetic association of tic disorders: a case-control study
대한소아청소년정신의학회 학술대회논문집
2022 .11
-
Exploring the Interplay of Tic Disorder, Heart Rate Variability, and Quality of Life in Adolescents
대한소아청소년정신의학회 학술대회논문집
2023 .11
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Effects of Group Comprehensive Behavioral Intervention for Tics in Children With Tourette’s Disorder and Chronic Tic Disorder
Na Ri Kang
,
Hui-Jeong Kim
,
Duk Soo Moon
외 1명
소아청소년정신의학
2022
.10
Dissociative Identity Disorder in an Adolescent With Nine Alternate Personality Traits: A Case Study
Sang-Hun Lee
,
Na Ri Kang
,
Duk-Soo Moon
소아청소년정신의학
2022
.07
What Event-Related Potential Tells Us about Brain Function: Child-Adolescent Psychiatric Perspectives
Ji Sun Kim
,
Yeon Jung Lee
,
Se-Hoon Shim
소아청소년정신의학
2021
.07
Affective Factors That Contribute to the Quality of Life of Juvenile Inmates with Attention-Deficit/Hyperactivity Disorder : A Focus on Items from the Korean Youth Self Report
Hyesoon Kim
,
Bongseog Kim
소아청소년정신의학
2019
.10
Clinical and Neuropsychological Factors Associated with Treatment Response and Adverse Events of Atomoxetine in Children with Attention-Deficit/Hyperactivity Disorder
Kee Jeong Pa
,
k
,
Hyo-Won Kim
소아청소년정신의학
2019
.04
최근 본 자료
댓글(0)
0