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자료유형
학술저널
저자정보
Kim Min-Gyeong (Oral Oncology Clinic Research Institute and Hospital National Cancer Center Goyang Korea) Choi Yong-Seok (Oral Oncology Clinic Research Institute and Hospital National Cancer Center Goyang Korea) Youn Suk Min (Oral Oncology Clinic Research Institute and Hospital National Cancer Center Goyang Korea) Ko Jae-Hee (Oral Oncology Clinic Research Institute and Hospital National Cancer Center Goyang Korea) Oh Hyun Jun (Oral Oncology Clinic Research Institute and Hospital National Cancer Center Goyang Korea) Lee Jong-Ho (Oral Oncology Clinic Research Institute and Hospital National Cancer Center Goyang KoreaDepartment) Park Joo-Yong (Oral Oncology Clinic Research Institute and Hospital National Cancer Center Goyang Korea) Choi Sung-Weon (Oral Oncology Clinic Research Institute and Hospital National Cancer Center Goyang Korea)
저널정보
대한구강악안면외과학회 대한구강악안면외과학회지 대한구강악안면외과학회지 제48권 제4호
발행연도
2022.8
수록면
192 - 200 (9page)
DOI
10.5125/jkaoms.2022.48.4.192

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Objectives: This study aimed to analyze the treatment outcomes and to evaluate the clinicopathological prognostic factors of oral tongue cancer. Patients and Methods: We retrospectively analyzed treatment results and prognostic factors in 205 patients with oral tongue squamous cell carcinoma who were admitted to the National Cancer Center, South Korea, between January 2001 and December 2020. The patients were treated with surgery and postoperative, definitive radiotherapy (RT) or chemoradiotherapy (CRT). Results: Eighteen patients (8.8%) were treated with curative RT or CRT, while the rest (91.2%) were treated with surgery with or without postoperative RT or CRT. The median follow-up period was 30 months (range, 0-234 months). The 5-year overall survival (OS) and 5-year disease-free survival (DFS) were 72% and 63%, respectively. Multivariate analysis revealed that a positive neck nodal status (N1, N2-3) was significantly associated with poorer 5-year OS and DFS, while perineural invasion was associated with poorer 5-year DFS. Conclusion: Cervical metastasis and perineural invasion are significant prognostic predictors, and combination treatments are necessary for improving OS and DFS in patients with these factors.

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