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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국약제학회 Journal of Pharmaceutical Investigation Journal of Pharmaceutical Investigation 제47권 제4호
- 발행연도
- 2017.7
- 수록면
- 297 - 316 (20page)
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초록· 키워드
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Spurred by the development in materials chemistry, stimuli-responsive nanocarriers that could show sharp responses to various environmental changes have found applications in many fields including controlled drug delivery in the past few years. Among all the available stimuli, light has recently attracted much attention owing to their non-invasiveness and the possibility of remote spatiotemporal control. A large amount of photoresponsive systems have been constructed to achieve on-demand drug, gene or other kinds of cytotoxic species release in responsive to illumination of a specific wavelength in near-infrared region (NIR), which shows better tissue penetration compared to visible or ultraviolet (UV) light with shorter wavelengths.
Exploration of NIR light-responsive therapeutic cargoes delivery systems opens up a new and exciting possibility for applications in nanomedicine. In this review article, we mainly focus on the recent progress in nanocarriers with different kinds of strategies to achieve NIR light-based control over the delivery process, with special emphasis on their application in NIR photo-response controlled therapeutic cargoes release and subsequent therapy.
The final section reviews current challenges in the use of NIR responsive nanomaterials and potential solutions.
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참고문헌 (149)
참고문헌 신청
배기현 / 2011 / Nanomaterials for Cancer Therapy and Imaging / Molecules and Cells 31(4):295~302
Barhoumi A / 2015 / Ultraviolet light-mediated drug delivery: principles, applications, and challenges / J Control Release 219:31~42
Burks P / 2013 / Nitric oxide releasing materials triggered by near-infrared excitation through tissue filters / J Am Chem Soc 135:18145~18152
Cao J / 2013 / Near-infrared light-triggered micelles for fast controlled drug release in deep tissue / Biomaterials 34:6272~6283
Cao J / 2016 / Multifunctional near-infrared light-triggered biodegradable micelles for chemo- and photo-thermal combination therapy / Oncotarget
Barhoumi A / 2015 / Ultraviolet light-mediated drug delivery: principles, applications, and challenges / J Control Release 219:31~42
Burks P / 2013 / Nitric oxide releasing materials triggered by near-infrared excitation through tissue filters / J Am Chem Soc 135:18145~18152
Cao J / 2013 / Near-infrared light-triggered micelles for fast controlled drug release in deep tissue / Biomaterials 34:6272~6283
Cao J / 2016 / Multifunctional near-infrared light-triggered biodegradable micelles for chemo- and photo-thermal combination therapy / Oncotarget
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