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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 201 - 206 (6page)
- DOI
- 10.5010/JPB.2021.48.3.201
이용수
초록· 키워드
오류제보하기
To ensure the safety of developing or importing genetically modified organisms (GMOs), Korea has enacted the “LMO Act.” Accordingly, the safety of using GMOs as food or feed is evaluated in accordance with the concept of “substantial equivalence” proposed by OECD. The allergenicity of GMOs is assessed as a part of their safety evaluation. The methods of allergenicity assessment have been discussed by various international organizations, such as the OECD, FAO, and WHO. The main methods used for the allergenicity assessment of proteins newly expressed in GMOs include assessment of the physicochemical stability of these proteins, evaluation of their amino acid homology with existing allergenic proteins, and serum screening. In this study, we describe guidelines and related studies for the allergenicity assessment of GM crops.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
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Altschul S F / 1997 / Gapped BLAST and PSI-BLAST : a new generation of protein database search programs / Nucleic Acids Research 25:3389~3402
Astwood, J.D. / 1996 / Stability of food allergens to digestion in vitro / Nature Biotechnology 14:1269~1273
Björkstén B / 1996 / Low-level exposure to house dust mites stimulates T-cell responses during early childhood independent of atopy / Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 26:775~779
Breiteneder, H. / 2005 / Molecular properties of food allergens / Journal of Allergy and Clinical Immunology 115:14~23
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