지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Purpureocillium lilacinum is a saprophytic fungus with a ubiquitous environmental distribution, and it can be detected in soil samples and decaying materials worldwide. It has been reported as an emerging pathogen in both immunocompromised and immunocompetent patients, showing various cutaneous presentations. Herein, we report a case of a patient with a localized cutaneous P. lilacinum infection, which resembles the skin lesions of psoriasis. A 72-year-old female was presented with a peripherally spreading, well-demarcated, asymptomatic, scaly, erythematous patch on her forehead for several months. Histopathological examination showed pinkish septated fungal elements and mixed inflammatory and granulomatous infiltrates in the dermis. Furthermore, a fungal culture on potato dextrose agar showed gray, velvety colonies with light yellow background after being subcultured. Phialides with chains of oval conidia were observed on lactophenol cotton blue staining. The ITS region of rRNA gene sequence obtained from the colony was identical to that of Purpureocillium lilacinum. The lesion was resolved with oral itraconazole (200 mg/day) after four months of treatment.
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참고문헌 (18)
참고문헌 신청
Luangsa-Ard J / 2011 / Purpureocillium, a new genus for the medically important Paecilomyces lilacinus / FEMS Microbiol Lett 321:141~149
Accetta J / 2020 / Isavuconazonium for the treatment of Purpureocillium lilacinum infection in a patient with pyoderma gangrenosum / Med Mycol Case Rep 29:18~21
Salazar-González MA / 2020 / Purpureocillium lilacinum as unusual cause of pulmonary infection in immunocompromised hosts / J Infect Dev Ctries 14:415~419
Chen WY / 2019 / Successful treatment of recur"rent cutaneous Purpureocillium lilacinum(Paecilomyces lilacinus)infection with posaconazole and surgical de"bridement / Acta Derm Venereol 99:1313~1314
Saghrouni F / 2013 / Cutaneous hyalohyphomycosis caused by Purpureocillium lilacinum in an immunocompetent patient:case report and review / Med Mycol 51:664~668
Accetta J / 2020 / Isavuconazonium for the treatment of Purpureocillium lilacinum infection in a patient with pyoderma gangrenosum / Med Mycol Case Rep 29:18~21
Salazar-González MA / 2020 / Purpureocillium lilacinum as unusual cause of pulmonary infection in immunocompromised hosts / J Infect Dev Ctries 14:415~419
Chen WY / 2019 / Successful treatment of recur"rent cutaneous Purpureocillium lilacinum(Paecilomyces lilacinus)infection with posaconazole and surgical de"bridement / Acta Derm Venereol 99:1313~1314
Saghrouni F / 2013 / Cutaneous hyalohyphomycosis caused by Purpureocillium lilacinum in an immunocompetent patient:case report and review / Med Mycol 51:664~668
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