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논문 기본 정보

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학술저널
저자정보
Burak Zeybek (Yale School of Medicine) Emily Webster (Yale School of Medicine) Natalia Pogosian (New York Institute of Technology College of Osteopathic Medicine) Joan Tymon-Rosario (Yale School of Medicine) Alan Balch (Patient Advocate Foundation) Gary Altwerger (Yale School of Medicine) Mitchell Clark (Yale School of Medicine) Gulden Menderes (Yale School of Medicine) Gloria Huang (Yale University School of Medicine) Masoud Azodi (Yale School of Medicine) Elena S. Ratner (Yale School of Medicine) Peter E. Schwartz (Yale University School of Medicine) Alessandro D. Santin (Yale School of Medicine) Vaagn Andikyan (Yale School of Medicine)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.32 No.6
발행연도
2021.11
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1 - 10 (10page)
DOI
https://doi.org/10.3802/jgo.2021.32.e87

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Objective: To evaluate financial toxicity and assess its risk factors among patients with gynecologic cancers. Methods: This is a cross sectional study that included 2 survey tools, as well as patient demographics, disease characteristics, and treatment regimen. Financial toxicity is measured by validated Comprehensive Score for Financial Toxicity (COST) tool. Participants were also asked to complete a 55-question-survey on attitudes and perspectives surrounding cost of care. Descriptive statistics was used to report patient demographics. Spearman's rank correlation was calculated to assess the relation between financial toxicity and patient/ disease related variables. Graphpad Prism Software Version 8.0 was used for analyses. Results: A total of 50 patients with various gynecologic malignancies were enrolled. Median COST score was 20.5 (range, 1?33). Sixty-five percent of the patients reported being in debt due to their cancer care and 4% filed bankruptcy. Correlation analysis showed that COST score was correlated with age (r=?0.3, p=0.028), malignancy type (r=0.3, p=0.039) and income (r=0.3, p=0.047). Ovarian cancer patients had significantly less financial toxicity (median COST score=23) when compared to patients with other gynecologic malignancies (median COST score=17, p=0.043). When scores were dichotomized into low (score ≥22) and high toxicity (score <22), 58% (29/50) of the patients were noted to have high financial toxicity. Enrollment to a clinical trial did not significantly alleviate financial burden. Conclusion: Financial toxicity is a significant burden even among highly insured gynecologic oncology patients. Age, malignancy type and income were correlated with high financial burden.
#Financial Stress #Ovarian Cancer #Uterine Cancer #Cervix Cancer #Vulva Cancer #Vagina Cancer

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참고문헌 (24)

참고문헌 신청
American Cancer Society / Global cancer facts & figures google schola WCRF International / Global cancer data by country google schola Mariotto AB / 2020 / Medical care costs associated with cancer survivorship in the United States / Cancer Epidemiol Biomarkers Prev 29:1304~1312 google schola Makker V / 2019 / Lenvatinib plus pembrolizumab in patients with advanced endometrial cancer: an interim analysis of a multicentre, open-label, single-arm, phase 2 trial / Lancet Oncol 20:711~718 google schola Tewari KS / 2017 / Bevacizumab for advanced cervical cancer: final overall survival and adverse event analysis of a randomised, controlled, open-label, phase 3 trial (Gynecologic Oncology Group 240) / Lancet 390:1654~1663 google schola

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