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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 1 - 11 (11page)
- DOI
- https://doi.org/10.3802/jgo.2021.32.e85
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초록· 키워드
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Objective: External beam radiation therapy (EBRT) with concurrent chemotherapy followed by intracavitary brachytherapy is the standard treatment in locally advanced cervical cancer. This study examined the brachytherapy utilization rate and evaluated the effect of brachytherapy on survival in cervical cancer patients in Korea.
Methods: In this study, data from the Korea Central Cancer Registry and Korean National Health Insurance Service and data on mortality from Statistics Korea were linked and used. Patients with other cancers, distant metastasis at diagnosis, or unknown stage or who underwent hysterectomy were excluded. A total of 12,721 cervical cancer patients were analyzed in this study.
Results: The brachytherapy utilization rate (%) was calculated as the proportion of patients who received brachytherapy among those who received curative EBRT. The brachytherapy utilization rate decreased from 84% in 2005 to 78% in 2013 (p<0.001). Brachytherapy utilization rates varied by region, ranging from 72% to 100% except for in Jeju Island, where the rate was 56%. The brachytherapy utilization rate was lower in patients older than 80 years; patients with localized disease, non-squamous cell carcinoma, or Charlson comorbidity index 3 or more; patients diagnosed after 2010; patients from certain regions; patients receiving medical aid; and patients who underwent gynecologic procedures. Multivariable Cox regression analysis showed that brachytherapy when added to curative EBRT was independently associated with better cancer-specific survival (CSS) and overall survival (OS) than curative EBRT only.
Conclusion: The brachytherapy utilization rate decreased from 2005 to 2013 and varied by region in Korea. Brachytherapy use is independently associated with significantly higher CSS and OS in cervical cancer.
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참고문헌 (17)
참고문헌 신청
홍세리 / 2020 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2017 / Cancer Research and Treatment 52(2):335~350
Al Feghali KA / 2016 / Why brachytherapy boost is the treatment of choice for most women with locally advanced cervical carcinoma? / Brachytherapy 15:191~199
Holschneider CH / 2019 / Brachytherapy: a critical component of primary radiation therapy for cervical cancer: From the Society of Gynecologic Oncology (SGO) and the American Brachytherapy Society (ABS) / Brachytherapy 18:123~132
Bauer-Nilsen K / 2018 / Evaluation of delivery costs for external beam radiation therapy and brachytherapy for locally advanced cervical cancer using time-driven activity-based costing / Int J Radiat Oncol Biol Phys 100:88~94
김해영 / 2016 / Current status of brachytherapy in Korea: a national survey of radiation oncologists / Journal of Gynecologic Oncology 27(4):1~11
Al Feghali KA / 2016 / Why brachytherapy boost is the treatment of choice for most women with locally advanced cervical carcinoma? / Brachytherapy 15:191~199
Holschneider CH / 2019 / Brachytherapy: a critical component of primary radiation therapy for cervical cancer: From the Society of Gynecologic Oncology (SGO) and the American Brachytherapy Society (ABS) / Brachytherapy 18:123~132
Bauer-Nilsen K / 2018 / Evaluation of delivery costs for external beam radiation therapy and brachytherapy for locally advanced cervical cancer using time-driven activity-based costing / Int J Radiat Oncol Biol Phys 100:88~94
김해영 / 2016 / Current status of brachytherapy in Korea: a national survey of radiation oncologists / Journal of Gynecologic Oncology 27(4):1~11
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