메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류
인문학
인문학 일반 역사학 철학 종교학 어문학 기타 인문학
사회과학
사회과학 일반 경영학 관광학 교육학 군사학 문헌정보학 법학 사회학 신문방송학 심리과학 정치외교학 지리학 행정학 경제학 무역학 인류학 기타 사회과학
자연과학
자연과학 일반 물리학 생물학 생활과학 수학·통계학 천문학 지구과학 화학 기타 자연과학
공학
공학 일반 건축공학 기계공학 산업공학 재료·에너지공학 전기전자공학 조선해양공학 화학공학 컴퓨터학 기타공학
의약학
의학 일반 간호학 수의학 약학 한의학 기초의학 임상의학 기타 의약학
농수해양학
농수해양학 일반 농학 수산학 식품과학 임학 축산학 해상운송학 기타 농수해양학
예술체육학
예술 일반 디자인 미술 미용 사진 음악학 의상 체육 공연매체예술 기타 예술체육학
복합학
학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

ENG

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Sharon J.B. Hanley (Hokkaido University Faculty of Medicine) Hiromasa Fujita (Hokkaido Cancer Society) Satomi Aoyama-Kikawa (Otaru General Hospital) Mitsunori Kasamo (Hokkaido Cancer Society) Toshihiko Torigoe (Sapporo Medical University) Yoshihiro Matsuno (Hokkaido University Hospital) Sakuragi Noriaki (Hokkaido University Faculty of Medicine)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.32 No.6
발행연도
2021.11
수록면
1 - 13 (13page)
DOI
https://doi.org/10.3802/jgo.2021.32.e86

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Objective: While cytology-based screening programs have significantly reduced mortality and morbidity from cervical cancer, the global consensus is that primary human papillomavirus (HPV) testing increases detection of high-grade cervical intraepithelial neoplasia (CIN) and invasive cancer. However, the optimal triage strategy for HPV+ women to avoid over-referral to colposcopy may be setting specific. We compared absolute and relative risk (RR) of >CIN2/3 within 12 months of a negative cytologic result in women HPV16/18+ compared to those with a 12-other high-risk HPV (hrHPV) genotype to identify women at greatest risk of high-grade disease and permit less aggressive management of women with other hrHPV infections. Methods: Participants were 14,160 women aged 25?69 years with negative cytology participating in the COMparison of HPV genotyping And Cytology Triage (COMPACT) study. Women who were HPV16/18+ were referred to colposcopy. Those with a 12-other hrHPV type underwent repeat cytology after 6 months and those with >abnormal squamous cells of undetermined significance went to colposcopy. Results: Absolute risk of >CIN2 in HPV16/18+ women was 19.5% (95% CI=12.4%?29.4%). In women 25?29 years and HPV16+ it was 40.0% (95% CI=11.8%?76.9%). Absolute risk of >CIN3 in women HPV16/18+ was 11.0% (95% CI=5.9%?19.6%). For women 30?39 years and HPV16+ it was 23.1% (95% CI=5.0%?53.8%). Overall risk of >CIN2, >CIN3 in women with a 12-other hrHPV HPV type was 5.6% (95% CI=3.1%?10.0%) and 3.4% (95% CI=1.6%?7.2%) respectively. RR of >CIN2, >CIN3 in HPV16/18+ vs. 12-other hrHPV was 3.5 (95% CI=1.7?7.3) and 3.3 (95% CI=1.2?8.8), respectively. Conclusion: Primary HPV screening with HPV16/18 partial genotyping is a promising strategy to identify women at current/future risk of >CIN2 in Japan without over-referral to colposcopy. Trial Registration: UMIN Clinical Trials Registry Identifier: UMIN000013203
#Cervical Cancer #Human Papillomavirus #Cytology #Cancer Screening

목차

등록된 정보가 없습니다.

참고문헌 (38)

참고문헌 신청
Peto J / 2004 / The cervical cancer epidemic that screening has prevented in the UK / Lancet 364:249~256 google schola Ronco G / 2014 / Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials / Lancet 383:524~532 google schola Sankaranarayanan R / 2009 / HPV screening for cervical cancer in rural India / N Engl J Med 360:1385~1394 google schola Isidean SD / 2016 / Human papillomavirus testing versus cytology in primary cervical cancer screening: End-of-study and extended follow-up results from the Canadian cervical cancer screening trial / Int J Cancer 139:2456~2466 google schola Cuschieri K / 2018 / Eurogin roadmap 2017: triage strategies for the management of HPV-positive women in cervical screening programs / Int J Cancer 143:735~745 google schola

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0