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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 127 - 134 (8page)
- DOI
- 10.5145/ACM.2021.24.4.3
이용수
이 논문의 연구 히스토리 (2)
2021
emm Types and Clusters of Group A Streptococcus Causing Acute Pharyngitis in Changwon Korea, 2018?2019
조선아
,
이승준
,
김선주
Annals of Clinical Microbiology
2021.12
학술저널
Clinical Manifestations of Bacterial Pharyngitis and Characteristics of Streptococcus pyogenes Pharyngeal Isolates in Southeastern Korea, 2018 -2019
조선아
의학과
2021.01
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초록· 키워드
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Background: Group A streptococcus (GAS) is the most common cause of bacterial pharyngitis.
This study aimed to characterize the molecular epidemiology of GAS infection using an emmtypingand emm-clustering approach.
Methods: A total of 372 patients from Changwon who showed pharyngitis symptoms wererecruited during the sampling period of 2018?2019 and throat cultures were obtainedfrom them. emm typing was performed using polymerase chain reaction (PCR) and directsequencing. emm genotypes and GAS clusters were classified based on a web-baseddatabase.
Results: Of the 372 throat swab specimens, 101 (27.2%) were positive for GAS. emm typinganalysis was performed on 59 GAS isolates. The most prevalent emm type was emm 89(20.3%), followed by emm 12 (16.9%). Seven emm clusters were identified: E4 (emm 89/emm28, 32.2%), A-C4 (emm12, 16.9%), E1 (emm4, 13.6%), A-C5 (emm3, 10.2%), E6 (emm75,8.5%), M6 (emm6, 8.5%), and A-C3 (emm1, 6.8%).
Conclusion: Diverse and temporal changes were observed in the distribution of emm typesand clusters of GAS. Continuous surveillance based on emm genotyping is needed to monitorthe epidemiological characteristics of GAS pharyngitis.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Rantala S / 2009 / Predictors of mortality in betahemolytic streptococcal bacteremia : a population-based study / J Infect 58:266~272
Steer AC / 2009 / Prospective surveillance of invasive group a streptococcal disease, Fiji, 2005-2007 / Emerg Infect Dis 15:216~222
Safar A / 2011 / Invasive group A streptococcal infection and vaccine implications, Auckland, New Zealand / Emerg Infect Dis 17:983~989
Carapetis JR / 2005 / The global burden of group A streptococcal diseases / Lancet Infect Dis 5:685~694
Walker MJ / 2014 / Disease manifestations and pathogenic mechanisms of Group A Streptococcus / Clin Microbiol Rev 27:264~301
Steer AC / 2009 / Prospective surveillance of invasive group a streptococcal disease, Fiji, 2005-2007 / Emerg Infect Dis 15:216~222
Safar A / 2011 / Invasive group A streptococcal infection and vaccine implications, Auckland, New Zealand / Emerg Infect Dis 17:983~989
Carapetis JR / 2005 / The global burden of group A streptococcal diseases / Lancet Infect Dis 5:685~694
Walker MJ / 2014 / Disease manifestations and pathogenic mechanisms of Group A Streptococcus / Clin Microbiol Rev 27:264~301
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