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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 212 - 219 (8page)
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Background: The molecular characterization of Streptococcus dysgalactiae subsp. equisimilis (SDSE) has not yet been performed in Korea. This study aimed to find the differences or similarities in the clinical features, molecular epidemiological findings, and antimicrobial resistance patterns of SDSE from two countries (Korea and Japan). Methods: SDSE isolates were collected from Korea (N=69) from 2012-2016 and Japan (N=71) from 2014-2016. Clinical characteristics, emm genotypes, and sequence types (STs) were compared. Microdilution tests were performed using different antimicrobials, and their resistance determinants were screened. Results: Median ages were 69 years in Korea and 76 years in Japan. The most common underlying diseases were diabetes and malignancy. Blood-derived isolates comprised 36.2% and 50.7% of Korean and Japanese isolates, respectively; mortality was not different between the two groups (5.8% vs 9.9%, P =0.53). Among Korean isolates with 20 different combined ST-emm types, ST127-stG245 (N=16), ST128-stG485 (N=10), and ST138- stG652 (N=8) were prevalent. Among Japanese isolates with 29 different combined types, ST17-stG6792 (N=11), ST29-stG485 (N=7), and ST205-stG6792 (N=6) were prevalent. Resistance rates to erythromycin, clindamycin, and minocycline were 34.8%, 17.4%, and 30.4% in Korea and 28.2%, 14.1%, and 21.4% in Japan, respectively. Conclusions: SDSE infections commonly occurred in elderly persons with underlying diseases. There was a significant difference in the distribution of ST-emm types between the two countries. Antimicrobial resistance rates were comparable with different frequencies of resistance determinants in each country.
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참고문헌 (25)
참고문헌 신청
Rantala S / 2014 / Streptococcus dysgalactiae subsp. equisimilis bacteremia: an emerging infection / Eur J Clin Microbiol Infect Dis 33:1303~1310
Brandt CM / 2009 / Human infections due to Streptococcus dysgalactiae subspecies equisimilis / Clin Infect Dis 49:766~772
손종애 / 2013 / 란스필드 그룹 A 양성인 Streptococcus dysgalactiae subsp. equisimilis / Laboratory Medicine Online 3(1):60~61
Wajima T / 2016 / Molecular characterization of invasive Streptococcus dysgalactiae subsp. equisimilis, Japan / Emerg Infect Dis 22:247~254
Bruun T / 2013 / Necrotizing soft tissue infections caused by Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis of groups C and G in western Norway / Clin Microbiol Infect 19:E545~E550
Brandt CM / 2009 / Human infections due to Streptococcus dysgalactiae subspecies equisimilis / Clin Infect Dis 49:766~772
손종애 / 2013 / 란스필드 그룹 A 양성인 Streptococcus dysgalactiae subsp. equisimilis / Laboratory Medicine Online 3(1):60~61
Wajima T / 2016 / Molecular characterization of invasive Streptococcus dysgalactiae subsp. equisimilis, Japan / Emerg Infect Dis 22:247~254
Bruun T / 2013 / Necrotizing soft tissue infections caused by Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis of groups C and G in western Norway / Clin Microbiol Infect 19:E545~E550
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