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논문 기본 정보

자료유형
학술저널
저자정보
Kim Hyun-Ju (Department of Psychiatry CHA Bundang Medical Center CHA University School of Medicine) Kim Ji Eun (Graduate School of Social Welfare Yonsei University) Lee Sang-Hyuk (Department of Psychiatry CHA Bundang Medical Center CHA University School of Medicine)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제18권 제9호
발행연도
2021.9
수록면
904 - 912 (9page)
DOI
10.30773/pi.2021.0227

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Objective Several predictors of unfavorable pharmacological treatment response (PTR) in panic disorder (PD) patients have been suggested, such as the duration of the illness, presence of agoraphobia, depression, being a woman, and early trauma. This study aimed to examine whether pathological worry is associated with PTR in PD patients.Methods This study included 335 PD patients and 418 healthy controls (HCs). The Penn State Worry Questionnaire (PSWQ), the Early Trauma Inventory Self Report-Short Form (ETISR-SF), Beck Depression Inventory (BDI), Panic Disorder Severity Scale (PDSS), and Anxiety Sensitivity Inventory-Revised (ASI-R) were administered. We measured the PTR at 8 weeks and 6 months. Student t-test, chisquare tests, Pearson’s correlation analyses, and binary logistic regression model were used.Results Our results showed that the total scores of the PSWQ correlated with the ETISR-SF, BDI, and ASI-R were significantly higher in patients with PD compared with HCs. The PSWQ and BDI could predict unfavorable PTR at 6 months in PD patients.Conclusion This is the first study to demonstrate that pathological worry may contribute to poor long-term PTR in PD patients. Therefore, our research suggests that clinicians must be aware of worry to optimize PTR for PD patients.

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