지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.12
- 수록면
- 51 - 56 (6page)
이용수
초록· 키워드
오류제보하기
Purpose: Neoadjuvant chemotherapy (NCT) is a treatment modality that increases the breast-conserving rate in breast cancer. This prospective study was performed to evaluate the actual breast-conserving rate using NCT in a clinical setting in a single institution. Methods: Between 2014 and 2015, 265 patients who were scheduled to receive NCT and surgery were enrolled in this study. Patients were classified into three groups based on the immunohistochemical results of estrogen receptor (ER)/progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2): ER or PR positive (luminal), ER/PR negative and HER2 positive (HER2+), and triple-negative breast cancer (TNBC). Before starting and immediately after completing NCT, a surgeon decided if breast-conserving surgery (BCS) or total mastectomy (TM) should be performed. We analyzed the rate of type of surgery performed. Results: Before administering NCT, 107 patients (40.4%) and 158 patients (59.6%) were candidates for BCS and TM, respectively. Of the 158 patients, 61 were eligible for BCS after chemotherapy, with a conversion rate of 38.6%. NCT increased the BCS eligible rate from 40.4% to 62.6%. Of the 61 patients, 53 chose to undergo BCS, and BCS was successful in 46 (86.8%). Of the 107 BCS candidates at baseline, 100 patents finally underwent BCS (93.5%). According to the subtype, the conversion rates were 35.4%, 50.0%, and 40.5% for luminal, HER2+, and TNBC groups, respectively. Conclusion: NCT increased the eligibility for BCS from 40.4% to 62.6% in a clinical setting. This benefit is similar to that observed in other clinical trials.
목차
등록된 정보가 없습니다.
참고문헌 (1)
참고문헌 신청
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
[Breast] Verification of New Nomogram for Predicting a Benefit of Neoadjuvant Chemotherapy in Korean Patients with Luminal Type A Breast Cancer Patients
대한외과학회 학술대회 초록집
2021 .11
-
[Breast] MRI in the Prediction of Pathological Complete Response in Breast Cancer Patients after Neoadjuvant Chemotherapy
대한외과학회 학술대회 초록집
2022 .11
-
Neoadjuvant Chemotherapy versus Adjuvant Chemotherapy in Breast Cancer Patients: Analysis of Breast Conserving Rate and De-escalation of Axillary Surgery in 5141 Korean Women
대한외과학회 학술대회 초록집
2020 .11
-
The Role of Neoadjuvant Chemotherapy in Patients with ER Positive and HER2 Negative Breast Cancer
대한외과학회 학술대회 초록집
2018 .11
-
Predictive and Prognostic Roles of Pathological Indicators for Patients with Breast Cancer on Neoadjuvant Chemotherapy
Journal of Breast Cancer
2019 .01
-
What Is Optimal Surgical Width and Margin for Breast Conserving Surgery after Neoadjuvant Chemotherapy?
대한외과학회 학술대회 초록집
2021 .11
-
Differences in prognosis by p53 expression after neoadjuvant chemotherapy in triple-negative breast cancer
Annals of Surgical Treatment and Research
2020 .06
-
Re-Excision Rate in Breast Conservation Surgery after Neoadjuvant Chemotherapy
Journal of Breast Disease
2017 .06
-
[Breast] Residual Tumor Degradation Patterns after Neoadjuvant Chemotherapy for Breast Cancer and Its Association with Clinicopathologic Factors and Prognosis
대한외과학회 학술대회 초록집
2021 .11
-
Prediction of Axillary Lymph Node Response Based on Breast Pathologic Complete Response and Breast Cancer Subtype after Neoadjuvant Chemotherapy
대한임상종양학회 학술대회지
2019 .02
-
[Breast] Risk Factors of Breast Cancer Recurrence in Pathologic Complete Response (pCR) Achieved Post Neoadjuvant Chemotherapy (NAC) Patients
대한외과학회 학술대회 초록집
2022 .11
-
The Basic Facts of Korean Breast Cancer in 2012: Results from a Nationwide Survey and Breast Cancer Registry Database
Journal of Breast Cancer
2015 .01
-
Breast Cancer Surgery on an Augmented Breast
대한외과학회 학술대회 초록집
2018 .11
-
Are the Outcomes of Breast Conservation Surgery Inferior to Those of Mastectomy in Patients with Stage II-IIIA Triple-Negative Breast Cancer?
Journal of Breast Disease
2021 .12
-
Predictive Factors of Pathologic N2/N3 Disease in Clinical or Pathologic N1 ER+/HER2- Breast Cancer
대한외과학회 학술대회 초록집
2023 .05
-
Breast Cancer
대한외과학회 학술대회 초록집
2022 .11
-
Tp53 Mutation Is Linked with High 21-Gene Recurrence Score in ER+/HER2- Breast Cancer
대한외과학회 학술대회 초록집
2021 .05
-
Breast Cancer
대한외과학회 학술대회 초록집
2020 .11
-
Breast Cancer
대한외과학회 학술대회 초록집
2022 .11
-
Breast Cancer
대한외과학회 학술대회 초록집
2020 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0