지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한수의학회 Korean Journal of Veterinary Research(대한수의학회지) Korean Journal of Veterinary Research(구 대한수의학회지) 제58권 제1호
- 발행연도
- 2018.5
- 수록면
- 9 - 16 (8page)
이용수
초록· 키워드
오류제보하기
A preliminary study into the protective mechanisms of adaptive immunity against porcine reproductive and respiratory syndrome virus (PRRSV) in piglets (n = 9) born to a gilt challenged intranasally with a type-2 PRRSV. Immune parameters (neutralizing antibodies, CD3<sup>+</sup>CD4<sup>+</sup>, CD3<sup>+</sup>CD8<sup>+</sup>, CD3<sup>+</sup>CD4<sup>+</sup>CD8<sup>+</sup> T-lymphocytes, and PRRSVspecific interferon (IFN)-γ secreting T-lymphocytes) were compared with infection parameters (macro- and microscopic lung lesion, and PRRSV-infected porcine alveolar macrophages (CD172α<sup>+</sup>PRRSV-N+ PAM) as well as with plasma and lymphoid tissue viral loads. Percentages of three T-lymphocyte phenotypes in 14-days post-birth (dpb) peripheral blood mononuclear cell (PBMC) had significant negative correlations with percentages of CD172α<sup>+</sup>PRRSV-N<sup>+</sup> PAM (p < 0.05) as well as with macroscopic lung lesion (p < 0.01). Plasma and tissue viral loads had significant (p < 0.05) negative correlations with CD3<sup>+</sup>CD4<sup>+</sup>CD8<sup>+</sup> T-lymphocyte percentage in PBMC. Frequencies of CD3<sup>+</sup>CD8<sup>+</sup> and CD3<sup>+</sup>CD4<sup>+</sup> T-lymphocytes in 14-dpb PBMC had significant negative correlations with of lymph node (p = 0.04) and lung (p = 0.002) viral loads. IFN-γ-secreting T-lymphocytes frequency had a significant negative correlation with gross lung lesion severity (p = 0.002). However, neutralizing antibody titers had no significant negative correlation (p > 0.1) with infection parameters. The results indicate that T-lymphocytes contribute to controlling PRRSV replication in young piglets born after in-utero infection.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Evaluation of virus suppression induced by PRRSV-specific T cells in type 1 PRRSV-infected pigs
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Age-specific Prevalence of Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus Type 2, and Mycoplasma hyopneumoniae in Korea Pig Farms
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2020 .03
-
Protection provided by a commercial modified-live porcine reproductive and respiratory syndrome virus (PRRSV) 1 vaccine (PRRSV1-MLV) against a Japanese PRRSV2 field strain
Journal of Veterinary Science
2023 .09
-
Circulating CCR7loPD-1hi Follicular Helper T Cells Indicate Disease Activity and Glandular Inflammation in Patients with Primary Sjögren’s Syndrome
Immune Network
2019 .08
-
Acute porcine reproductive and respiratory syndrome outbreaks in immunized sow herds: from occurrence to stabilization under whole herd vaccination strategy
Korean Journal of Veterinary Research(대한수의학회지)
2018 .07
-
Genetic diversity and phylogenetic analysis of porcine reproductive and respiratory syndrome virus in southern China from 2007 to 2014
Journal of Veterinary Science
2017 .09
-
Transcriptome profiling identifies immune response genes against porcine reproductive and respiratory syndrome virus and Haemophilus parasuis co-infection in the lungs of piglets
Journal of Veterinary Science
2022 .01
-
A rapid and quantitative fluorescent microsphere immunochromatographic strip test for detection of antibodies to porcine reproductive and respiratory syndrome virus
Journal of Veterinary Science
2020 .07
-
Curcumin Elevates TFH Cells and Germinal Center B Cell Response for Antibody Production in Mice
Immune Network
2019 .10
-
T cells-mediated immune response induced by chimeric virus expressing porcine reproductive and respiratory syndrome virus(PRRSV)-derived peptides
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Development of an immunochromatographic strip for detection of antibodies against porcine reproductive and respiratory syndrome virus
Journal of Veterinary Science
2017 .09
-
Co-infection of Toxoplasma gondii and porcine reproductive and respiratory syndrome virus in suckling piglets in Jeju, Korea
한국가축위생학회지
2020 .01
-
Phenotypic and genotypic analyses of an attenuated porcine reproductive and respiratory syndrome virus strain after serial passages in cultured porcine alveolar macrophages
Journal of Veterinary Science
2018 .05
-
A new recombined porcine reproductive and respiratory syndrome virus virulent strain in China
Journal of Veterinary Science
2018 .01
-
PRRS 양성농장의 사육단계별 구강액과 혈액을 이용한 PRRSV와 항체 검출 비교
한국가축위생학회지
2020 .01
-
돼지생식기호흡기증후군바이러스(PRRSV)의 전장 유전체 염기서열(whole-genome sequencing) 분석을 위한 차세대 염기서열 분석법의 활용
한국가축위생학회지
2016 .01
-
Ortho-phenylphenol을 주성분으로 하는 훈증소독제의 돼지열병바이러스와 돼지생식기호흡기증후군바이러스에 대한 살바이러스 효과
한국가축위생학회지
2016 .01
-
A standardized method to study immune responses using porcine whole blood
Journal of Veterinary Science
2023 .01
-
Development of a multiplex qRT-PCR assay for detection of African swine fever virus, classical swine fever virus and porcine reproductive and respiratory syndrome virus
Journal of Veterinary Science
2021 .11
-
Duplex nested reverse transcriptase polymerase chain reaction for simultaneous detection of type 2 porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 from tissue samples
Journal of Veterinary Science
2017 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-528-001375227