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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제26권 제12호
- 발행연도
- 2016.12
- 수록면
- 2,030 - 2,035 (6page)
- DOI
- 10.4014/jmb.1604.04094
이용수
이 논문의 연구 히스토리 (4)
2016
Genome Sequence of Bacillus cereus FORC_021, a Food-Borne Pathogen Isolated from a Knife at a Sashimi Restaurant
Han Young Chung
,
이규호
,
SANGRYEOLRYU
외 7명
Journal of Microbiology and Biotechnology
2016.12
학술저널
Complete Genome Analysis of Vibrio parahaemolyticus FORC_023, Isolated from Storage Water for Raw Fish
Han Young Chung
,
Byungho Lee
,
Eun Jung Na
외 1명
한국미생물학회 학술대회논문집
2016.04
학술대회자료
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초록· 키워드
오류제보하기
Bacillus cereus causes food-borne illness through contaminated foods; therefore, its pathogenicity and genome sequences have been analyzed in several studies. We sequenced and analyzed B. cereus strain FORC_021 isolated from a sashimi restaurant. The genome sequence consists of 5,373,294 bp with 35.36% GC contents, 5,350 predicted CDSs, 42 rRNA genes, and 107 tRNA genes. Based on in silico DNA-DNA hybridization values, B. cereus ATCC 14579T was closest to FORC_021 among the complete genome-sequenced strains. Three major enterotoxins were detected in FORC_021. Comparative genomic analysis of FORC_021 with ATCC 14579T revealed that FORC_021 harbored an additional genomic region encoding virulence factors, such as putative ADP-ribosylating toxin, spore germination protein, internalin, and sortase. Furthermore, in vitro cytotoxicity testing showed that FORC_021 exhibited a high level of cytotoxicity toward INT-407 human epithelial cells. This genomic information of FORC_021 will help us to understand its pathogenesis and assist in managing food contamination.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Andersson A / 1995 / What problems does the food industry have with the spore-forming pathogens Bacillus cereus and Clostridium perfringens? / Int. J. Food Microbiol 28:145~155
Ash C / 1991 / Comparative analysis of Bacillus anthracis, Bacillus cereus, and related species on the basis of reverse transcriptase sequencing of 16S rRNA / Int. J. Syst. Bacteriol 41:343~346
Bohm ME / 2015 / Massivehorizontal gene transfer, strictly vertical inheritance and ancient duplications differentially shape the evolution of Bacillus cereus enterotoxin operons hbl, cytK and nhe / BMC Evol. Biol 15:246
Ceuppens S / 2012 / Survival and germination of Bacillus cereus spores without outgrowth or enterotoxin production during in vitro simulation of gastrointestinal transit / Appl. Environ. Microbiol 78:7698~7705
Cascioferro S / 2014 / Sortase A: an ideal target for anti-virulence drug development / Microb. Pathog 77:105~112
Ash C / 1991 / Comparative analysis of Bacillus anthracis, Bacillus cereus, and related species on the basis of reverse transcriptase sequencing of 16S rRNA / Int. J. Syst. Bacteriol 41:343~346
Bohm ME / 2015 / Massivehorizontal gene transfer, strictly vertical inheritance and ancient duplications differentially shape the evolution of Bacillus cereus enterotoxin operons hbl, cytK and nhe / BMC Evol. Biol 15:246
Ceuppens S / 2012 / Survival and germination of Bacillus cereus spores without outgrowth or enterotoxin production during in vitro simulation of gastrointestinal transit / Appl. Environ. Microbiol 78:7698~7705
Cascioferro S / 2014 / Sortase A: an ideal target for anti-virulence drug development / Microb. Pathog 77:105~112
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