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자료유형
학술저널
저자정보
강혜승 (세경대학교) 배은숙 (서라벌대학교) 허정이 (세경대학교)
저널정보
아태인문사회융합기술교류학회 아시아태평양융합연구교류논문지 아시아태평양융합연구교류논문지 제9권 제5호
발행연도
2023.5
수록면
589 - 599 (11page)
DOI
http://dx.doi.org/10.47116/apjcri.2023.05.49

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Diabetic nephropathy (DN) is a major complication occurring in type 2 diabetic(T2DM) patients and characterized by persistent albuminuria and decreased renal function. Microalbuminuria (MAU) is a well-known early marker of DN in T2DM patients. This study aimed to analyse the possible associations among glycated hemoglobin (HbA1c), daily vitamin C(ascorbic acid) intake, and urinary microalbumin, as predictors of DN in T2DM patients. The cross-sectional study was utilized to analyze the secondary data from the National Health and Nutrition Examination Survey. The study population comprised 510 patients who were not diagnosed with hypertension prior to T2DM. Statistical analysis was done by using R 3.5.1 version and this study analyzed by simple linear and stepwise multiple regression. Among patients with T2DM, 19.0% had MAU, 75.7% had nomoalbuminuria, and 5.3% had macroalbuminuria. The value of HbA1c was significantly higher in patients with MAU and macroalbuminuria than in normoalbuminuria. As a result of the study, microalbuminuria was predicted by HbA1c and there was an interaction between daily vitamin C intake and HbA1c. This means that microalbuminuria is a risk marker for DN and is associated with HbA1c and vitamin C. Therefore, in type 2 diabetic patients, periodic screening of blood glucose and high-dose vitamin C intake are required for preventing MAU and DN.

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