메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Kwon Jae Wan (Department of Internal Medicine Kyungpook National University Hospital School of Medicine Kyungpook National University Daegu Korea) Jeon Yena (Department of Pathology Kyungpook National University Hospital School of Medicine Kyungpook National University Daegu Korea) Jung Hee-Yeon (Department of Internal Medicine Kyungpook National University Hospital School of Medicine Kyungpook National University Daegu Korea) 최지영 (경북대학교) 박선희 (경북대학교) 김찬덕 (경북대학교) 김용림 (경북대학교) Hwang Deokbi (Department of Surgery Kyungpook National University Hospital School of Medicine Kyungpook National University Daegu Korea) 윤우성 (경북대학교) 김형기 (경북대학교) 허승 (경북대학교) 유은상 (경북대학교) 원동일 (경북대학교) 조장희 (경북대학교) 임정훈 (경북대학교)
저널정보
대한이식학회 Clinical Transplantation and Research Korean Journal of Transplantation Vol.37 No.1
발행연도
2023.3
수록면
19 - 28 (10page)
DOI
10.4285/kjt.22.0047

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background: The C-reactive protein (CRP)-to-albumin ratio (CAR) is a more effective prognostic indicator than CRP or albumin alone in various diseases. This study aimed to evaluate the predictive value of the CAR for mortality in kidney transplant recipients (KTRs). Methods: A total of 924 patients who underwent their f irst kidney transplantation at Kyungpook National University Hospital during 2006–2020 were enrolled and classified into quartile (Q) groups according to their pretransplant CAR values. A Cox regression analysis was conducted to analyze the hazard ratios (HRs) of mortality. Results: Fifty-nine patients died during the posttransplant period (mean, 85.2±44.2 months). All-cause mortality (Q1, 3.0%; Q2, 4.8%; Q3, 7.8%; Q4, 10.0%; P for trend <0.001) and infection-related mortality increased linearly with an increase in CAR (P for trend=0.004). The Q3 and Q4 had higher risks of all-cause mortality than Q1 after adjusting for confounding factors (Q3: adjusted HR [aHR] 2.49, 95% confidence interval [CI] 1.04–5.99, P=0.041; Q4: aHR 3.09, 95% CI 1.31–7.27, P=0.010). Q4 was also independently associated with infection-related mortality (aHR 5.83, 95% CI 1.27–26.8, P=0.023). The area under the curve of the CAR for all-cause and infection-related mortality was higher than that of CRP or albumin alone. There was no association between CAR and death-censored graft failure or acute rejection. Conclusions: A higher pretransplant CAR increases the risk of posttransplant mortality, particularly infection-related, in KTRs. Pretransplant CAR can be an effective and easily accessible predictor of posttransplant mortality.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0